iPTMnet Report for Q14118 (DAG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14118 / DAG1_HUMAN
Protein Name Dystroglycan 1 precursor
Gene Name Name: DAG1
Organism Homo sapiens (Human)

PRO ID PR:Q14118
DAG View
PRO Name dystroglycan 1 (human)
Definition A dystroglycan 1 that is encoded in the genome of human.
Short Label hDAG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14118 (DAG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 O-Glycosylation GlyGen 25813380
S49 O-Glycosylation GlyGen 25813380
S52 O-Glycosylation GlyGen 25813380
T63 O-Glycosylation GlyGen   UniProt 30459171, 25813380, 23234360
Y130 Phosphorylation PhosphoSitePlus
N141 N-Glycosylation GlyGen 23090970, 24190977
T169 O-Glycosylation GlyGen 25813380
S171 O-Glycosylation GlyGen 25813380
S216 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
T317 O-Glycosylation GlyGen   UniProt 21987822, 24256719
T319 O-Glycosylation GlyGen   UniProt 21987822, 24256719
T343 O-Glycosylation GlyGen 30459171
T367 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 20507882, 25813380
T369 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 20507882, 25813380
T372 O-Glycosylation GlyGen   UniProt 20507882
T379 O-Glycosylation GlyGen   UniProt 20044576, 25813380, 23723439
T381 O-Glycosylation GlyGen   UniProt 20044576, 25813380
T388 O-Glycosylation GlyGen   UniProt 20044576, 25813380
S391 O-Glycosylation GlyGen 25813380
T414 Phosphorylation PhosphoSitePlus
S430 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T431 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K433 Ubiquitination PhosphoSitePlus
T436 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S438 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T439 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S441 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T442 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T443 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T444 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T445 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T446 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T450 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T455 O-Glycosylation GlyGen   UniProt 20507882
T463 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 30379171, ...25813380, 31492838, 34019948, 23584533
T464 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 30379171, ...25813380, 31492838, 34019948, 23584533
S467 Phosphorylation PhosphoSitePlus
T469 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T469 Phosphorylation PhosphoSitePlus
T473 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T473 Phosphorylation PhosphoSitePlus
S475 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S475 Phosphorylation PhosphoSitePlus
T478 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T478 Phosphorylation PhosphoSitePlus
T482 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T483 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T484 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S485 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S485 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
K626 Methylation PhosphoSitePlus
N641 N-Glycosylation GlyGen 23090970, 24190977
N649 N-Glycosylation GlyGen 23090970, 24190977
N661 N-Glycosylation GlyGen   UniProt 29741879, 18764929
K687 Ubiquitination PhosphoSitePlus
S729 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T734 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
K780 Ubiquitination PhosphoSitePlus
K782 Ubiquitination PhosphoSitePlus
T784 Phosphorylation PhosphoSitePlus
T790 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K793 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus
S814 Phosphorylation PhosphoSitePlus
Y863 Phosphorylation PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
T884 O-Glycosylation GlyGen 23301498, 30379171, 31492838, ...33214551, 34019948
T884 Phosphorylation PhosphoSitePlus
Y886 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
Y892 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 11495720, 20512930, 12795607
Y892 Phosphorylation P12931 (SRC) phospho.ELM   Signor 12795607
Site PTM Type PTM Enzyme Score Source PMID
N661 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S216 I216 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S218 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S218 L218 Biomuta DOID:1324 / lung cancer [ cosmic ]
T369 S369 Biomuta [ cosmic ]
T379 I379 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T414 A414 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T436 M436 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T436 A436 Biomuta DOID:1324 / lung cancer [ cosmic ]
T439 A439 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y575 H575 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S729 L729 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y892 C892 Biomuta DOID:10534 / stomach cancer [ cosmic ]