Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14117 / DPYS_HUMAN
Protein Name Dihydropyrimidinase
Gene Name Name: DPYS
Organism Homo sapiens (Human)

PRO ID PR:Q14117
DAG View
PRO Name dihydropyrimidinase (human)
Definition A dihydropyrimidinase that is encoded in the genome of human.
Short Label hDPYS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14117 (DPYS) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S79 Phosphorylation PhosphoSitePlus   UniProt 24275569
K409 Acetylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
K501 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K409 E409 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T484 A484 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]