Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14116 / IL18_HUMAN
Protein Name Interleukin-18 precursor
Gene Name Name: IL18
Synonyms:IGIF,IL1F4;
Organism Homo sapiens (Human)

PRO ID PR:Q14116
DAG View
PRO Name interleukin-18 (human)
Definition An interleukin-18 that is encoded in the genome of human.
Short Label hIL18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14116 (IL18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y37 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K120 Acetylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y37 * Biomuta DOID:1115 / sarcoma [ tcga ]