iPTMnet Report for Q14112 (NID2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14112 / NID2_HUMAN
Protein Name Nidogen-2 precursor
Gene Name Name: NID2
Organism Homo sapiens (Human)

PRO ID PR:Q14112
DAG View
PRO Name nidogen-2 (human)
Definition A nidogen-2 that is encoded in the genome of human.
Short Label hNID2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14112 (NID2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S358 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S359 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S359 Phosphorylation PhosphoSitePlus
T360 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T365 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T369 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T369 Phosphorylation PhosphoSitePlus
S370 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T391 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S393 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T410 O-Glycosylation GlyGen 30459171
S419 O-Glycosylation GlyGen 30459171
S431 O-Glycosylation GlyGen 30459171
S448 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
Y449 Phosphorylation PhosphoSitePlus
S452 O-Glycosylation GlyGen   PhosphoSitePlus   UniProt 23584533, 32337544
T455 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T456 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S459 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S459 Phosphorylation PhosphoSitePlus
T462 O-Glycosylation GlyGen 30459171
T475 O-Glycosylation GlyGen 30459171
T479 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
T502 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
T506 Phosphorylation PhosphoSitePlus
N658 N-Glycosylation GlyGen 29741879
N693 N-Glycosylation GlyGen 29741879
N703 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T773 Phosphorylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
T846 O-Glycosylation GlyGen 30459171
T934 O-Glycosylation GlyGen 30459171
T994 O-Glycosylation GlyGen 30459171
T1012 O-Glycosylation GlyGen 30459171
T1087 O-Glycosylation GlyGen 30459171
T1096 O-Glycosylation GlyGen 30459171
T1102 O-Glycosylation GlyGen 30459171
T1113 O-Glycosylation GlyGen 30459171
N1124 N-Glycosylation GlyGen   UniProt 19159218
S1218 Phosphorylation PhosphoSitePlus
T1331 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S359 F359 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T360 N360 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T365 N365 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T369 I369 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S370 F370 Biomuta DOID:4159 / skin cancer [ cosmic ]
S370 Y370 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S431 L431 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S452 L452 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T456 I456 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T462 M462 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T479 M479 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
T502 M502 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y504 C504 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T506 S506 Biomuta DOID:1324 / lung cancer [ cosmic ]
T773 I773 Biomuta DOID:1324 / lung cancer [ cosmic ]
S816 C816 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1012 I1012 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1096 A1096 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1096 M1096 Biomuta DOID:2394 / ovarian cancer [ cosmic ]