Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14108 / SCRB2_HUMAN
Protein Name Lysosome membrane protein 2
Gene Name Name: SCARB2
Organism Homo sapiens (Human)

PRO ID PR:Q14108
DAG View
PRO Name lysosome membrane protein 2 (human)
Definition A lysosome membrane protein 2 that is encoded in the genome of human.
Short Label hSCARB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14108 (SCARB2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
N45 N-Glycosylation UniProt 24162852, 19159218
N68 N-Glycosylation UniProt 24162852, 19159218
Y89 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
N105 N-Glycosylation UniProt 19159218
N206 N-Glycosylation UniProt 24162852, 19159218
N224 N-Glycosylation UniProt 24162852
N249 N-Glycosylation UniProt 24162852, 12754519, 19159218
S282 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
Y284 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
N304 N-Glycosylation UniProt 24162852, 19159218
N325 N-Glycosylation UniProt 24162852, 19159218
T373 Phosphorylation PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
N412 N-Glycosylation UniProt 24162852, 12754519
S463 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
T478 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y388 Phosphorylation HPRD 18452278

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S282 R282 Biomuta DOID:3571 / liver cancer [ icgc ]
N325 Y325 Biomuta DOID:1324 / lung cancer [ cosmic ]
T373 I373 Biomuta DOID:2394 / ovarian cancer [ icgc ] DOID:2994 / germ cell cancer [ cosmic ]
K391 N391 Biomuta DOID:1612 / breast cancer [ tcga ]
S463 F463 Biomuta DOID:1793 / pancreatic cancer [ tcga ]