Protein Information

Cytoscape View

UniProt AC / UniProt ID Q14061 / COX17_HUMAN
Protein Name Cytochrome c oxidase copper chaperone
Gene Name Name: COX17
Organism Homo sapiens (Human)

PRO ID PR:Q14061
DAG View
PRO Name cytochrome c oxidase copper chaperone (human)
Definition A cytochrome c oxidase copper chaperone that is encoded in the genome of human.
Short Label hCOX17
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q14061 (COX17) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S14 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K17 Acetylation PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
K31 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ] DOID:3571 / liver cancer [ icgc ]
K30 N30 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]