iPTMnet Report for Q14012 (CAMK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14012 / KCC1A_HUMAN
Protein Name Calcium/calmodulin-dependent protein kinase type 1
Gene Name Name: CAMK1
Organism Homo sapiens (Human)

PRO ID PR:Q14012
DAG View
PRO Name calcium/calmodulin-dependent protein kinase type 1 (human)
Definition A calcium/calmodulin-dependent protein kinase type 1 that is encoded in the genome of human.
Short Label hCAMK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14012 (CAMK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y20 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus   UniProt 23707388
Y131 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
T177 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23110126, 11395482, 9822657, ...17287469, 23216827, 8253780, 15173201, 15262966, 7641687
T177 Phosphorylation Q14012 (CAMK1) HPRD 7641687
T177 Phosphorylation Q8N5S9 (CAMKK1) neXtProt   PhosphoSitePlus 15173201, 17287469, 7641687
T177 Phosphorylation Q96RR4 (CAMKK2) HPRD   neXtProt 9822657, 23110126, 11395482
Y235 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus   UniProt 24275569


Q14012 (CAMK1) as PTM Enzyme



Substrate Site Score Source PMID
O43432 (EIF4G3) S1156 HPRD   neXtProt   PhosphoSitePlus   Signor 14507913
P05783 (KRT18) S53 Signor 7523419
P17600-2 (SYN1) S9 HPRD   neXtProt 12237306, 9395448, 10571231, ...8022798
P18846 (ATF1) S63 HPRD   neXtProt 8621702, 20068231, 8663317
P24844 (MYL9) S20 neXtProt   PhosphoSitePlus 12081505
P29475-1 (NOS1) S746 HPRD   neXtProt 15251453
P29475-1 (NOS1) S852 HPRD 10874031, 12630910, 1375933, ...10400690
P39019 (RPS19) S59 neXtProt   PhosphoSitePlus 19200342
P46527 (CDKN1B) T157 PhosphoSitePlus 23707388
P46527 (CDKN1B) T198 PhosphoSitePlus 23707388
P49757 (NUMB) S276 neXtProt   Signor 17022975
P49757 (NUMB) S295 neXtProt 17022975
P57059 (SIK1) T322 neXtProt 17939993
Q05469 (LIPE) S855 PhosphoSitePlus 2537200
Q14012 (CAMK1) T177 HPRD 7641687
Q14155 (ARHGEF7) S694 neXtProt 18184567
Q7KZI7 (MARK2) S91 neXtProt 17442826
Q7KZI7 (MARK2) S92 neXtProt 17442826
Q7KZI7 (MARK2) S93 neXtProt 17442826
Q7KZI7 (MARK2) T294 neXtProt 17442826
Q9NP62 (GCM1) S47 neXtProt   PhosphoSitePlus   Signor 21791615
Q9UKV0 (HDAC9) S220 PhosphoSitePlus 20188095
Q9UKV0 (HDAC9) S451 PhosphoSitePlus 20188095
Q9UQL6 (HDAC5) S259 HPRD   neXtProt   PhosphoSitePlus   Signor 11114197, 11081517, 15367659
Q9UQL6-3 (HDAC5) S260 HPRD 11114197, 11081517, 15367659
Q9UQL6 (HDAC5) S498 HPRD   neXtProt   PhosphoSitePlus   Signor 11114197, 11081517, 15367659
Q9UQL6-3 (HDAC5) S499 HPRD 11114197, 11081517, 15367659
Q9UQM7-2 (CAMK2A) S332 PhosphoSitePlus 9677407
Q9Y570 (PPME1) S15 Signor 24841198


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y131 C131 Biomuta DOID:1319 / brain cancer [ cosmic ]