iPTMnet Report for Q14005 (IL16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q14005 / IL16_HUMAN
Protein Name Pro-interleukin-16
Gene Name Name: IL16
Organism Homo sapiens (Human)

PRO ID PR:Q14005
DAG View
PRO Name pro-interleukin-16 (human)
Definition An interleukin-16 that is encoded in the genome of human.
Short Label hIL16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q14005 (IL16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S139 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
T298 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
Y516 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
S743 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 12450396
T757 Phosphorylation P06493 (CDK1) neXtProt   PhosphoSitePlus 12450396
Y771 Phosphorylation PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
S804 Phosphorylation PhosphoSitePlus
S833 Phosphorylation PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus
S836 Phosphorylation PhosphoSitePlus
S844 Phosphorylation PhosphoSitePlus
S845 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) PhosphoSitePlus   Signor 14768064
T848 Phosphorylation PhosphoSitePlus
S851 Phosphorylation PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
K857 Ubiquitination PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
R882 Methylation PhosphoSitePlus
S884 Phosphorylation PhosphoSitePlus
R889 Methylation PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus
S922 Phosphorylation PhosphoSitePlus   UniProt 24275569
T933 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
T947 Phosphorylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
S961 Phosphorylation PhosphoSitePlus
S966 Phosphorylation PhosphoSitePlus
T970 Phosphorylation PhosphoSitePlus
S972 Phosphorylation PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
K978 Methylation PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
S995 Phosphorylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S1001 O-Glycosylation GlyGen 27655845, 29351928
S1001 Phosphorylation PhosphoSitePlus
S1074 Phosphorylation PhosphoSitePlus
S1247 Phosphorylation PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus
K1259 Ubiquitination PhosphoSitePlus
S1275 O-Glycosylation GlyGen 27655845, 29351928
T1277 O-Glycosylation GlyGen 27655845, 29351928
K1305 Ubiquitination PhosphoSitePlus
S1320 Phosphorylation PhosphoSitePlus
K1324 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S743 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD 12450396
T757 Phosphorylation P06493 (CDK1) HPRD 12450396
S863 Phosphorylation HPRD 20166139
S920 Phosphorylation HPRD 20058876
S922 Phosphorylation HPRD 20058876
S946 Phosphorylation HPRD 20166139, 20058876
Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation P19784 (CSNK2A2) , P68400 (CSNK2A1) HPRD 12450396
T56 Phosphorylation P06493 (CDK1) HPRD 12450396
S162 Phosphorylation HPRD 20166139
S219 Phosphorylation HPRD 20058876
S221 Phosphorylation HPRD 20058876
S245 Phosphorylation HPRD 20166139, 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S221 C221 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S221 F221 Biomuta DOID:10283 / prostate cancer [ cosmic ]