iPTMnet Report for Q13948 (CUX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13948 / CASP_HUMAN
Protein Name Protein CASP
Gene Name Name: CUX1
Synonyms:CUTL1;
Organism Homo sapiens (Human)

PRO ID PR:Q13948
DAG View
PRO Name protein CASP isoforms CASP/h8/h9/h10 (human)
Definition A protein CASP (human), isoforms CASP, h8, h9, and h10.
Short Label hCUX1/iso:[CASP/8/9/10]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


Q13948 (CUX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S333 Phosphorylation PhosphoSitePlus
S374 Phosphorylation IEDB 35494241
T429 Phosphorylation PhosphoSitePlus
T434 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
R570 Methylation PhosphoSitePlus
Y575 Phosphorylation PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus   UniProt 23186163
K587 Ubiquitination PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S333 Phosphorylation HPRD 17525332
S402 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S331 Phosphorylation HPRD 17525332
S400 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S331 R331 Biomuta DOID:263 / kidney cancer [ cosmic ]
S333 R333 Biomuta DOID:263 / kidney cancer [ cosmic ]
S400 L400 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S402 L402 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T429 N429 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T436 I436 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S503 F503 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K546 Q546 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S586 R586 Biomuta DOID:10534 / stomach cancer [ cosmic ]