iPTMnet Report for Q13889 (GTF2H3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13889 / TF2H3_HUMAN
Protein Name General transcription factor IIH subunit 3
Gene Name Name: GTF2H3
Organism Homo sapiens (Human)

PRO ID PR:Q13889
DAG View
PRO Name general transcription factor IIH subunit 3 (human)
Definition A general transcription factor IIH subunit 3 that is encoded in the genome of human.
Short Label hGTF2H3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13889 (GTF2H3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K28 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K125 Sumoylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
C142 Methylation IEDB 31844290
K152 Ubiquitination PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
C268 Methylation IEDB 31844290
K298 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T129 Phosphorylation HPRD 20068231
Y143 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K116 N116 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K121 N121 Biomuta DOID:1612 / breast cancer [ cosmic ]
C268 Y268 Biomuta DOID:1319 / brain cancer [ cosmic ]