iPTMnet Report for Q13887 (KLF5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13887 / KLF5_HUMAN
Protein Name Krueppel-like factor 5
Gene Name Name: KLF5
Synonyms:BTEB2,CKLF,IKLF;
Organism Homo sapiens (Human)

PRO ID PR:Q13887
DAG View
PRO Name krueppel-like factor 5 (human)
Definition A krueppel-like factor 5 that is encoded in the genome of human.
Short Label hKLF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13887 (KLF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K31 Ubiquitination PhosphoSitePlus
R57 Methylation PhosphoSitePlus
K110 Sumoylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S153 O-Glycosylation GlyGen 33214551, 30059200, 35289036, ...34019948
S153 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 28032601, 12682370
S153 Phosphorylation Q05655 (PRKCD) Signor 12682370
T159 O-Glycosylation GlyGen 33214551, 30059200, 35289036, ...34019948
K162 Sumoylation PhosphoSitePlus
K209 Sumoylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 28480051, 20484041, 24398687
S303 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 20484041, 24398687
T323 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
Y359 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
K369 Acetylation PhosphoSitePlus
Y377 Phosphorylation PhosphoSitePlus
K391 Sumoylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
T396 Phosphorylation PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S116 Phosphorylation HPRD 18452278
S153 Phosphorylation HPRD 12682370
S153 Phosphorylation Q05655 (PRKCD) HPRD 12682370
S441 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S153 F153 Biomuta DOID:4159 / skin cancer [ cosmic ]
S303 P303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S303 L303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S303 A303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T346 S346 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T398 A398 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S441 N441 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]