Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13838 / DX39B_HUMAN
Protein Name Spliceosome RNA helicase DDX39B
Gene Name Name: DDX39B
Synonyms:BAT1,UAP56;
Organism Homo sapiens (Human)

PRO ID PR:Q13838
DAG View
PRO Name spliceosome RNA helicase DDX39B (human)
Definition A spliceosome RNA helicase BAT1 that is encoded in the genome of human.
Short Label hDDX39B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13838 (DDX39B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
Y13 Phosphorylation PhosphoSitePlus
T20 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K36 Acetylation PhosphoSitePlus   UniProt 19608861
K36 Ubiquitination PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
Y39 Phosphorylation PhosphoSitePlus
S41 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S44 Phosphorylation PhosphoSitePlus
K53 Acetylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
R58 Methylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K162 Acetylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
C165 S-Nitrosylation dbSNO 22178444
T172 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K183 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
R208 Methylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
Y265 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
K334 Acetylation PhosphoSitePlus
K334 Sumoylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
R339 Methylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
R349 Methylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
Y371 Phosphorylation PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
K398 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y13 Phosphorylation HPRD 19413330, 18491316, 19664995
S38 Phosphorylation HPRD 19651622, 20068231
S41 Phosphorylation HPRD 19651622, 20068231
T172 Phosphorylation HPRD 19651622, 18669648, 20068231
S228 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y266 C266 Biomuta DOID:2531 / hematologic cancer [ icgc ]
R339 Q339 Biomuta DOID:3070 / malignant glioma [ tcga ]
R339 * Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
R349 * Biomuta DOID:363 / uterine cancer [ tcga ]
K398 N398 Biomuta DOID:363 / uterine cancer [ tcga ]