iPTMnet Report for Q13829 (TNFAIP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13829 / BACD2_HUMAN
Protein Name BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Gene Name Name: TNFAIP1
Synonyms:BACURD2,EDP1;
Organism Homo sapiens (Human)

PRO ID PR:Q13829
DAG View
PRO Name BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (human)
Definition A BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 that is encoded in the genome of human.
Short Label hTNFAIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13829 (TNFAIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
S278 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19851886, 16565220, ...18669648, 20068231
S278 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 19851886
S280 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 18669648, 23186163, 19851886
S280 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19851886
T285 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S278 Phosphorylation HPRD 18669648, 20068231, 16565220
S280 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K21 N21 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y256 C256 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc, tcga ]