iPTMnet Report for Q13823 (GNL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13823 / NOG2_HUMAN
Protein Name Nucleolar GTP-binding protein 2
Gene Name Name: GNL2
Synonyms:NGP1;
Organism Homo sapiens (Human)

PRO ID PR:Q13823
DAG View
PRO Name nucleolar GTP-binding protein 2 (human)
Definition A nucleolar GTP-binding protein 2 that is encoded in the genome of human.
Short Label hGNL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13823 (GNL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K16 Methylation PhosphoSitePlus
R23 Methylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K242 Sumoylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
T409 O-Glycosylation GlyGen 36240223, 32522876, 28510447
K411 Ubiquitination PhosphoSitePlus
S414 O-Glycosylation GlyGen 36240223, 32522876, 28510447
K424 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
K507 Sumoylation PhosphoSitePlus
T510 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S553 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
S561 Phosphorylation HPRD 17081983, 18452278
S563 Phosphorylation HPRD 17081983, 18452278
S580 Phosphorylation HPRD   PhosphoSitePlus 18452278
S581 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
S582 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18452278
K603 Acetylation PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
Y698 Phosphorylation PhosphoSitePlus
Y699 Phosphorylation PhosphoSitePlus
K705 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R23 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R23 Q23 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K58 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
T442 I442 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K507 R507 Biomuta DOID:4159 / skin cancer [ cosmic ]
K507 T507 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S582 P582 Biomuta DOID:1324 / lung cancer [ cosmic ]
S582 L582 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K705 E705 Biomuta DOID:9256 / colorectal cancer [ cosmic ]