iPTMnet Report for Q13822 (ENPP2)
Protein Information
| UniProt AC / UniProt ID | Q13822 / ENPP2_HUMAN |
| Protein Name | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 precursor |
| Gene Name | Name: ENPP2 Synonyms:ATX; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13822 |
| PRO Name | ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) |
| Definition | An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 that is encoded in the genome of human. |
| Short Label | hENPP2 |
| Category | organism-gene |
DAG ViewQ13822 (ENPP2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T210 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 8798697 | ||
| T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N411 | N-Glycosylation | score1 | GlyGen | 29741879, 29391424 | ||
| T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y462 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N524 | N-Glycosylation | score2 | GlyGen | 17307740 | ||
| N525 | N-Glycosylation | score3 | GlyGen UniProt | 26371182 | ||
| Y599 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y606 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y694 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y846 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T210 | Phosphorylation | score1 | HPRD | 8798697 | ||
| K356 | Acetylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T596 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S302 | L302 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S302 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S308 | C308 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K356 | Q356 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| N525 | I525 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y606 | F606 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] |
