iPTMnet Report Q13769 THOC5

Protein Information

UniProt AC / UniProt ID	Q13769 / THOC5_HUMAN
Protein Name	THO complex subunit 5 homolog
Gene Name	Name: THOC5 Synonyms:C22orf19,KIAA0983;
Organism	Homo sapiens (Human)

PRO ID	PR:Q13769 DAG View
PRO Name	THO complex subunit 5 homolog (human)
Definition	A THO complex subunit 5 that is encoded in the genome of human.
Short Label	hTHOC5
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q13769 (THOC5) as Substrate

Q13769

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S2 S3 S5 S6 S16 K24 S28 T30 Y37 K56 S74 K146 K175 S210 K217 Y225 S293 S307 S312 S314 T321 T322 T328 K336 S347 K412 Y420 K477 K514 C630	PTM Type Select all Acetylation Methylation O-Glycosylation Phosphorylation Ubiquitination	PTM Enzyme Select all P09619 (PDGFRB) P17252 (PRKCA)	Score Select all 0 1 2 3 4	Source Select all GlyGen HPRD IEDB PhosphoSitePlus RLIMS-P Signor UniProt phospho.ELM	PMID
S2	Acetylation		score1	UniProt	22814378
S2	O-Glycosylation		score1	GlyGen	30379171, 34019948
S2	Phosphorylation		score0	HPRD	20068231
S3	Phosphorylation		score0	HPRD	20068231
S5	Phosphorylation		score3	HPRD phospho.ELM PhosphoSitePlus Signor	15221008
S5	Phosphorylation	P17252 (PRKCA)	score3	HPRD PhosphoSitePlus Signor	15221008
S6	Phosphorylation		score4	HPRD phospho.ELM PhosphoSitePlus Signor	15221008, 20068231
S6	Phosphorylation	P17252 (PRKCA)	score4	HPRD PhosphoSitePlus Signor	15221008, 20068231
S16	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
K24	Acetylation		score1	PhosphoSitePlus
S28	Phosphorylation		score1	PhosphoSitePlus
T30	Phosphorylation		score1	PhosphoSitePlus
Y37	Phosphorylation		score1	PhosphoSitePlus
K56	Ubiquitination		score1	PhosphoSitePlus
S74	O-Glycosylation		score1	GlyGen	30379171, 34019948
K146	Ubiquitination		score1	PhosphoSitePlus
K175	Ubiquitination		score1	PhosphoSitePlus
S210	Phosphorylation		score1	PhosphoSitePlus
K217	Ubiquitination		score1	PhosphoSitePlus
Y225	Phosphorylation		score4	PhosphoSitePlus RLIMS-P UniProt	18373705, 26919114, 23032722
Y225	Phosphorylation	P09619 (PDGFRB)	score2	PhosphoSitePlus	18373705
S293	Phosphorylation		score1	PhosphoSitePlus
S307	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus UniProt	17525332, 21406692, 18452278, ...18669648, 24275569, 20166139, 19690332, 20068231
S312	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 21406692, 23186163, ...17081983, 17525332, 18452278, 19651622, 18669648, 19415658, 24275569, 20166139, 19690332, 20068231
S314	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus UniProt	19413330, 17525332, 23186163, ...17081983, 21406692, 18452278, 19651622, 18669648, 19690332, 24275569, 20166139, 19415658, 20068231
T321	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus	18669648
T322	Phosphorylation		score2	HPRD phospho.ELM	18669648
T328	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	23186163, 20068231, 24275569
K336	Ubiquitination		score1	PhosphoSitePlus
S347	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
K412	Ubiquitination		score1	PhosphoSitePlus
Y420	Phosphorylation		score1	PhosphoSitePlus
K477	Ubiquitination		score1	PhosphoSitePlus
K514	Ubiquitination		score1	PhosphoSitePlus
C630	Methylation		score1	IEDB	31844290

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S5 Y37 K146 K217 T322 Y420	Variant Select all A322 C37 L5 M322 N146 N217 S420	Source Select all Biomuta	Disease [Sample source] Select all DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S5	L5	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y37	C37	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
K146	N146	Biomuta	DOID:363 / uterine cancer [ cosmic, icgc ]
K217	N217	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
T322	M322	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T322	A322	Biomuta	DOID:2531 / hematologic cancer [ cosmic ]
Y420	S420	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q13769 (THOC5)

Protein Information

Interactive Sequence View

Q13769 (THOC5) as Substrate

PTM sites affected in variants