iPTMnet Report for Q13753 (LAMC2)
Protein Information
| UniProt AC / UniProt ID | Q13753 / LAMC2_HUMAN |
| Protein Name | Laminin subunit gamma-2 precursor |
| Gene Name | Name: LAMC2 Synonyms:LAMB2T,LAMNB2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13753 |
| PRO Name | laminin subunit gamma-2 (human) |
| Definition | A laminin subunit gamma-2 that is encoded in the genome of human. |
| Short Label | hLAMC2 |
| Category | organism-gene |
Q13753 (LAMC2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y250 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| Y265 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| Y273 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| N342 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| N362 | N-Glycosylation | score1 | GlyGen | 23090970, 24190977 | ||
| K636 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S686 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T762 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| S767 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S771 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S773 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T779 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K787 | Acetylation | score1 | PhosphoSitePlus | |||
| K819 | Acetylation | score1 | PhosphoSitePlus | |||
| T831 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T835 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T886 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| N942 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S977 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S987 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S999 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1094 | O-Glycosylation | score1 | GlyGen | 25813380 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y273 | D273 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S767 | R767 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T779 | K779 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S999 | R999 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View