Protein Information

Cytoscape View

UniProt AC / UniProt ID Q13740 / CD166_HUMAN
Protein Name CD166 antigen precursor
Gene Name Name: ALCAM
Organism Homo sapiens (Human)

PRO ID PR:Q13740
DAG View
PRO Name CD166 antigen (human)
Definition A CD166 molecule that is encoded in the genome of human.
Short Label hALCAM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q13740 (ALCAM) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S64 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
N91 N-Glycosylation UniProt 12754519, 19159218
N95 N-Glycosylation UniProt 16335952, 19159218
N167 N-Glycosylation UniProt 12754519
Y199 Phosphorylation PhosphoSitePlus
N265 N-Glycosylation UniProt 16335952
Y298 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
N457 N-Glycosylation UniProt 19159218, 19349973
N480 N-Glycosylation UniProt 12754519, 19159218
N499 N-Glycosylation UniProt 16335952, 12754519
K559 Acetylation PhosphoSitePlus
K563 Acetylation PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S501 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N95 D95 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
N265 S265 Biomuta DOID:363 / uterine cancer [ tcga ]
N457 S457 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
N480 I480 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K572 Q572 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K573 E573 Biomuta DOID:1793 / pancreatic cancer [ tcga ]