iPTMnet Report for Q13740 (ALCAM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13740 / CD166_HUMAN
Protein Name CD166 antigen precursor
Gene Name Name: ALCAM
Synonyms:MEMD;
Organism Homo sapiens (Human)

PRO ID PR:Q13740
DAG View
PRO Name CD166 antigen (human)
Definition A CD166 molecule that is encoded in the genome of human.
Short Label hALCAM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13740 (ALCAM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S64 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
N91 N-Glycosylation GlyGen   UniProt 29741879, 12754519, 29391424, ...19159218, 24190977
N95 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19159218, ...24190977
N167 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 12754519, ...24190977
Y199 Phosphorylation PhosphoSitePlus
N265 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 24190977, ...29391424, 29741879
Y298 Phosphorylation PhosphoSitePlus
N306 N-Glycosylation GlyGen 29741879, 29391424, 24190977
T308 Phosphorylation PhosphoSitePlus
N361 N-Glycosylation GlyGen 23090970, 29741879, 29671580, ...29391424, 24190977
N457 N-Glycosylation GlyGen   UniProt 19159218, 19349973
N480 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 12754519, ...19159218, 24190977
N496 N-Glycosylation GlyGen 24190977
N499 N-Glycosylation GlyGen   UniProt 16335952, 12754519, 29671580, ...24190977
K559 Acetylation PhosphoSitePlus
K563 Acetylation PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N167 N-Glycosylation PRO 29741879
N265 N-Glycosylation PRO 29741879
N361 N-Glycosylation PRO 29741879, 29671580
N480 N-Glycosylation PRO 29741879
N499 N-Glycosylation PRO 29671580
Site PTM Type PTM Enzyme Score Source PMID
S501 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N91 S91 Biomuta DOID:1324 / lung cancer [ cosmic ]
N95 D95 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y199 H199 Biomuta DOID:4159 / skin cancer [ cosmic ]
N265 S265 Biomuta DOID:363 / uterine cancer [ icgc ]
N457 S457 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
N480 I480 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K572 Q572 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K573 E573 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]