iPTMnet Report for Q13733 (ATP1A4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13733 / AT1A4_HUMAN
Protein Name Sodium/potassium-transporting ATPase subunit alpha-4
Gene Name Name: ATP1A4
Synonyms:ATP1AL2;
Organism Homo sapiens (Human)

PRO ID PR:Q13733
DAG View
PRO Name sodium/potassium-transporting ATPase subunit alpha-4 (human)
Definition A sodium/potassium-transporting ATPase subunit alpha-4 that is encoded in the genome of human.
Short Label hATP1A4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13733 (ATP1A4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
R235 Methylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus
T261 Phosphorylation PhosphoSitePlus
E295 Methylation IEDB 34433824
H298 Methylation IEDB 34433824
K367 Ubiquitination PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
T418 Phosphorylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
T623 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S949 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S85 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K45 R45 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K164 E164 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K164 M164 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R235 H235 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R235 C235 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S236 F236 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S236 Y236 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T240 S240 Biomuta DOID:1319 / brain cancer [ cosmic ]
E295 K295 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T386 M386 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]