Protein Information

Cytoscape View

UniProt AC / UniProt ID Q13705 / AVR2B_HUMAN
Protein Name Activin receptor type-2B precursor
Gene Name Name: ACVR2B
Organism Homo sapiens (Human)

PRO ID PR:Q13705
DAG View
PRO Name activin receptor type-2B (human)
Definition An activin receptor type-2B that is encoded in the genome of human.
Short Label hACVR2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q13705 (ACVR2B) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
N42 N-Glycosylation GlyGen   UniProt 22718755
N65 N-Glycosylation GlyGen   UniProt 22718755
K224 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus

Q13705 (ACVR2B) as PTM Enzyme

Substrate Site Score Source PMID
P36896 (ACVR1B) T206 Signor 8622651

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036443 (hACVR2B/iso:ActR-IIB2/NGlycoPhos:1) Interaction PR:Q9UNH7 (hSNX6) PRO 11279102, 9872992

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K240 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]