iPTMnet Report for Q13651 (IL10RA)
Protein Information
| UniProt AC / UniProt ID | Q13651 / I10R1_HUMAN |
| Protein Name | Interleukin-10 receptor subunit alpha precursor |
| Gene Name | Name: IL10RA Synonyms:IL10R; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13651 |
| PRO Name | interleukin-10 receptor subunit alpha (human) |
| Definition | An interleukin-10 receptor subunit alpha that is encoded in the genome of human. |
| Short Label | hIL10RA |
| Category | organism-gene |
DAG ViewQ13651 (IL10RA) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N110 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N154 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N177 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K183 | Acetylation | score1 | PhosphoSitePlus | |||
| S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S319 | Phosphorylation | score0 | RLIMS-P | 22087322 | ||
| S323 | Phosphorylation | score0 | RLIMS-P | 22087322 | ||
| S370 | Phosphorylation | score0 | RLIMS-P | 22087322 | ||
| Y446 | Phosphorylation | P23458 (JAK1) , P29597 (TYK2) | score3 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 10433356 | |
| Y496 | Phosphorylation | P29597 (TYK2) , P23458 (JAK1) | score3 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 10433356 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q13651 (IL10RA) | S323 | Q9Y297 (BTRC) | unknown | eFIP | 22087322 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N110 | K110 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K183 | N183 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
