iPTMnet Report for Q13643 (FHL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13643 / FHL3_HUMAN
Protein Name Four and a half LIM domains protein 3
Gene Name Name: FHL3
Synonyms:SLIM2;
Organism Homo sapiens (Human)

PRO ID PR:Q13643
DAG View
PRO Name four and a half LIM domains protein 3 (human)
Definition A four and a half LIM domains protein 3 that is encoded in the genome of human.
Short Label hFHL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13643 (FHL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
K9 Sumoylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
K157 Sumoylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T168 O-Glycosylation GlyGen 29485866, 30379171
T193 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 N2 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S13 Y13 Biomuta DOID:10283 / prostate cancer [ icgc ]
S13 F13 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T168 M168 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]