iPTMnet Report for Q13641 (TPBG)
Protein Information
UniProt AC / UniProt ID | Q13641 / TPBG_HUMAN |
Protein Name | Trophoblast glycoprotein precursor |
Gene Name | Name: TPBG Synonyms:5T4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13641 |
PRO Name | trophoblast glycoprotein (human) |
Definition | A trophoblast glycoprotein that is encoded in the genome of human. |
Short Label | hTPBG |
Category | organism-gene |
Q13641 (TPBG) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S50 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S53 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T99 | Phosphorylation | score1 | PhosphoSitePlus | |||
N124 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
N275 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y399 | Phosphorylation | score1 | PhosphoSitePlus | |||
S415 | Phosphorylation | score0 | HPRD | 20068231 | ||
S416 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S418 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N275 | H275 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S416 | C416 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |