Protein Information

Cytoscape View

UniProt AC / UniProt ID Q13614 / MTMR2_HUMAN
Protein Name Myotubularin-related protein 2
Gene Name Name: MTMR2
Organism Homo sapiens (Human)

PRO ID PR:Q13614
DAG View
PRO Name myotubularin-related protein 2 (human)
Definition A myotubularin-related protein 2 that is encoded in the genome of human.
Short Label hMTMR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q13614 (MTMR2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
C7 S-Nitrosylation dbSNO 26338901
T30 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
T52 Phosphorylation PhosphoSitePlus
S58 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 23378027, 21372139, ...31537807, 19690332
K69 Ubiquitination PhosphoSitePlus
K137 Acetylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S631 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 18669648, 23378027
T637 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T641 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S58 Phosphorylation HPRD 19413330, 18669648, 18452278
S630 Phosphorylation HPRD 17081983, 20068231
S631 Phosphorylation HPRD 18669648, 17081983, 20068231, ...19664995
Site PTM Type PTM Enzyme Score Source PMID
S558 Phosphorylation HPRD 17081983, 20068231
S559 Phosphorylation HPRD 18669648, 17081983, 20068231, ...19664995

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 R6 Biomuta DOID:1115 / sarcoma [ tcga ]
S33 L33 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
T171 K171 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K610 Q610 Biomuta DOID:1909 / melanoma [ cosmic ]