iPTMnet Report for Q13596 (SNX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13596 / SNX1_HUMAN
Protein Name Sorting nexin-1
Gene Name Name: SNX1
Organism Homo sapiens (Human)

PRO ID PR:Q13596
DAG View
PRO Name sorting nexin-1 (human)
Definition A sorting nexin-1 that is encoded in the genome of human.
Short Label hSNX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13596 (SNX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S25 Phosphorylation phospho.ELM 18669648
S32 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S39 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
T41 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S54 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y131 Phosphorylation PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
S188 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 24275569, ...19690332, 20068231
Y194 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K237 Acetylation PhosphoSitePlus   UniProt 19608861
K237 Ubiquitination PhosphoSitePlus
R262 Methylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K286 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
Y502 Phosphorylation PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S39 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
T41 Phosphorylation HPRD 18669648, 17081983, 18452278
T48 Phosphorylation HPRD 18669648, 17081983
S72 Phosphorylation HPRD 19651622
S188 Phosphorylation HPRD 20166139, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation HPRD 18669648, 20068231
S32 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S39 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
T41 Phosphorylation HPRD 18669648, 17081983, 18452278
T48 Phosphorylation HPRD 18669648, 17081983
S72 Phosphorylation HPRD 19651622
S123 Phosphorylation HPRD 20166139, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 P3 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T41 A41 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S54 N54 Biomuta DOID:1319 / brain cancer [ icgc ]
S64 F64 Biomuta DOID:4159 / skin cancer [ cosmic ]
S123 G123 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S188 G188 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y194 H194 Biomuta DOID:4159 / skin cancer [ cosmic ]
T276 I276 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K286 N286 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K490 N490 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]