iPTMnet Report for Q13574 (DGKZ)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13574 / DGKZ_HUMAN
Protein Name Diacylglycerol kinase zeta
Gene Name Name: DGKZ
Synonyms:DAGK6;
Organism Homo sapiens (Human)

PRO ID PR:Q13574
DAG View
PRO Name diacylglycerol kinase zeta (human)
Definition A diacylglycerol kinase zeta that is encoded in the genome of human.
Short Label hDGKZ
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13574 (DGKZ) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S705 Phosphorylation UniProt 23186163
S781 Phosphorylation UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
K312 Acetylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
T443 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
Y529 Phosphorylation PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
Y673 Phosphorylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
T771 Phosphorylation PhosphoSitePlus
T779 Phosphorylation PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
Y845 Phosphorylation PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
T896 Phosphorylation PhosphoSitePlus
S901 Phosphorylation PhosphoSitePlus
S957 Phosphorylation PhosphoSitePlus
T961 Phosphorylation PhosphoSitePlus
S962 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
S970 Phosphorylation PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
T1022 Phosphorylation PhosphoSitePlus
S1024 Phosphorylation PhosphoSitePlus
K1025 Ubiquitination PhosphoSitePlus
T1061 Phosphorylation PhosphoSitePlus
Y1065 Phosphorylation PhosphoSitePlus
T1082 Phosphorylation PhosphoSitePlus
K1089 Ubiquitination PhosphoSitePlus
Y1105 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S282 Phosphorylation P17252 (PRKCA) HPRD 9716136
S514 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S266 Phosphorylation P17252 (PRKCA) HPRD 9716136
S498 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S76 G76 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S193 L193 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T260 I260 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S498 F498 Biomuta DOID:3571 / liver cancer [ cosmic ]
S514 F514 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y529 C529 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S841 N841 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K1025 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
T1082 I1082 Biomuta DOID:4606 / bile duct cancer [ cosmic ]