iPTMnet Report for Q13510 (ASAH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13510 / ASAH1_HUMAN
Protein Name Acid ceramidase precursor
Gene Name Name: ASAH1
Synonyms:ASAH;ORFNames:HSD-33,HSD33;
Organism Homo sapiens (Human)

PRO ID PR:Q13510
DAG View
PRO Name acid ceramidase (human)
Definition An acid ceramidase that is encoded in the genome of human.
Short Label hASAH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13510 (ASAH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
Y43 Phosphorylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
N170 N-Glycosylation GlyGen 24190977
N173 N-Glycosylation GlyGen   UniProt 29692406
N195 N-Glycosylation GlyGen 24190977
T197 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
N259 N-Glycosylation GlyGen   UniProt 16335952, 34089345, 19159218, ...24190977, 16263699, 29692406, 29741879, 12754519
K272 Ubiquitination PhosphoSitePlus
N286 N-Glycosylation GlyGen   UniProt 19159218, 24190977, 26791533, ...29692406, 29741879, 12754519
K299 Ubiquitination PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
Y305 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
N342 N-Glycosylation GlyGen   UniProt 29741879, 29692406, 24190977
N348 N-Glycosylation GlyGen 29741879, 24190977
S359 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N286 N-Glycosylation PRO 26791533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S39 * Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]
S90 N90 Biomuta DOID:184 / bone cancer [ cosmic ]
T197 S197 Biomuta DOID:1319 / brain cancer [ cosmic ]
N259 S259 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K299 N299 Biomuta DOID:363 / uterine cancer [ cosmic ]
K310 Q310 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]