iPTMnet Report for Q13496 (MTM1)
Protein Information
| UniProt AC / UniProt ID | Q13496 / MTM1_HUMAN |
| Protein Name | Myotubularin |
| Gene Name | Name: MTM1 Synonyms:CG2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13496 |
| PRO Name | myotubularin (human) |
| Definition | A myotubularin that is encoded in the genome of human. |
| Short Label | hMTM1 |
| Category | organism-gene |
DAG ViewQ13496 (MTM1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18088087, 23186163 | ||
| S18 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S91 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S106 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y260 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T495 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 16964243 | ||
| K546 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T587 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S588 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| S590 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S591 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S593 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S13 | Phosphorylation | score0 | HPRD | 18088087 | ||
| S18 | Phosphorylation | score0 | HPRD | 20166139 | ||
| T495 | Phosphorylation | score0 | HPRD | 16964243 | ||
| S583 | Phosphorylation | score0 | HPRD | 17081983 | ||
| T587 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S588 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S590 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S591 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T601 | Phosphorylation | score0 | HPRD | 17081983 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y9 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S13 | Y13 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K20 | N20 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S91 | P91 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S106 | F106 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K236 | N236 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K236 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K252 | I252 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S297 | T297 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| T495 | A495 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K546 | N546 | Biomuta | [ cosmic ] |
