iPTMnet Report for Q13490 (BIRC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13490 / BIRC2_HUMAN
Protein Name Baculoviral IAP repeat-containing protein 2
Gene Name Name: BIRC2
Synonyms:API1,MIHB,RNF48;
Organism Homo sapiens (Human)

PRO ID PR:Q13490
DAG View
PRO Name baculoviral IAP repeat-containing protein 2 (human)
Definition A baculoviral IAP repeat-containing protein 2 that is encoded in the genome of human.
Short Label hBIRC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13490 (BIRC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 O-Glycosylation GlyGen 30379171
K19 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S140 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S147 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S157 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y177 Phosphorylation PhosphoSitePlus
S178 O-Glycosylation GlyGen 30379171
K226 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
K497 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S140 Phosphorylation HPRD 18669648
S147 Phosphorylation HPRD 18669648
S157 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K102 N102 Biomuta DOID:1612 / breast cancer [ cosmic ]
K126 N126 Biomuta DOID:1612 / breast cancer [ cosmic ]
S178 I178 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S178 G178 Biomuta [ cosmic ]
K233 N233 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S253 Y253 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K441 N441 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K490 E490 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S580 Y580 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]