Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13489 / BIRC3_HUMAN
Protein Name Baculoviral IAP repeat-containing protein 3
Gene Name Name: BIRC3
Synonyms:API2,MIHC,RNF49;
Organism Homo sapiens (Human)

PRO ID PR:Q13489
DAG View
PRO Name baculoviral IAP repeat-containing protein 3 (human)
Definition A baculoviral IAP repeat-containing protein 3 that is encoded in the genome of human.
Short Label hBIRC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13489 (BIRC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
K596 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 I7 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
Y245 * Biomuta DOID:363 / uterine cancer [ tcga ]
S248 C248 Biomuta DOID:2394 / ovarian cancer [ icgc, tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S278 R278 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
T398 I398 Biomuta DOID:363 / uterine cancer [ tcga ]