iPTMnet Report for Q13454 (TUSC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13454 / TUSC3_HUMAN
Protein Name Tumor suppressor candidate 3 precursor
Gene Name Name: TUSC3
Synonyms:N33;
Organism Homo sapiens (Human)

PRO ID PR:Q13454
DAG View
PRO Name tumor suppressor candidate 3 (human)
Definition A tumor suppressor candidate 3 that is encoded in the genome of human.
Short Label hTUSC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13454 (TUSC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R63 Methylation PhosphoSitePlus
R67 Methylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
S327 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R63 C63 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R63 H63 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R63 L63 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R67 Q67 Biomuta [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R67 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S331 * Biomuta DOID:1319 / brain cancer [ cosmic ]