iPTMnet Report for Q13443 (ADAM9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13443 / ADAM9_HUMAN
Protein Name Disintegrin and metalloproteinase domain-containing protein 9 precursor
Gene Name Name: ADAM9
Synonyms:KIAA0021,MCMP,MDC9,MLTNG;
Organism Homo sapiens (Human)

PRO ID PR:Q13443
DAG View
PRO Name disintegrin and metalloproteinase domain-containing protein 9 (human)
Definition A disintegrin and metalloproteinase domain-containing protein 9 that is encoded in the genome of human.
Short Label hADAM9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13443 (ADAM9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K85 Ubiquitination PhosphoSitePlus
N125 N-Glycosylation GlyGen 23090970, 24190977
N144 N-Glycosylation GlyGen 23090970, 24190977
N154 N-Glycosylation GlyGen 23090970, 24190977
S156 O-Glycosylation GlyGen 34846842
K184 Acetylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
N381 N-Glycosylation GlyGen 29741879
S383 O-Glycosylation GlyGen 34846842, 34019948, 35289036, ...35254053
S384 O-Glycosylation GlyGen 34846842, 34019948, 35289036, ...35254053
S386 O-Glycosylation GlyGen 34846842
K392 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
K533 Acetylation PhosphoSitePlus
C539 Methylation IEDB 31844290
K546 Ubiquitination PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
T735 Phosphorylation PhosphoSitePlus
Y736 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
S758 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S758 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
T761 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T761 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
Y769 Phosphorylation PhosphoSitePlus
R772 Methylation PhosphoSitePlus
T777 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T777 Phosphorylation PhosphoSitePlus
Y778 Phosphorylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
K796 Ubiquitination PhosphoSitePlus
S798 O-Glycosylation GlyGen 34846842, 34019948, 35289036, ...35254053
S798 Phosphorylation PhosphoSitePlus
S799 Phosphorylation PhosphoSitePlus
Y815 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S816 Phosphorylation PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus
T819 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y213 Phosphorylation HPRD 19664994
S758 Phosphorylation HPRD 19651622, 18578522, 18669648, ...20068231, 17081983
T761 Phosphorylation HPRD 19651622, 18767875, 18669648, ...17081983, 20068231
Y769 Phosphorylation HPRD 19651622, 19901323
Y815 Phosphorylation HPRD 18083107, 19901323


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N154 Y154 Biomuta DOID:3571 / liver cancer [ cosmic ]
S379 F379 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S384 N384 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S386 R386 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K533 N533 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K546 R546 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S798 P798 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S817 F817 Biomuta DOID:1324 / lung cancer [ cosmic ]