iPTMnet Report for Q13433 (SLC39A6)
Protein Information
| UniProt AC / UniProt ID | Q13433 / S39A6_HUMAN |
| Protein Name | Zinc transporter ZIP6 precursor |
| Gene Name | Name: SLC39A6 Synonyms:LIV1,ZIP6; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13433 |
| PRO Name | zinc transporter ZIP6 (human) |
| Definition | A zinc transporter ZIP6 that is encoded in the genome of human. |
| Short Label | hSLC39A6 |
| Category | organism-gene |
Q13433 (SLC39A6) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T32 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T33 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| N67 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19349973, ... | ||
| N68 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S185 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T188 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S189 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T190 | O-Glycosylation | score1 | GlyGen | 30459171, 25813380 | ||
| Y192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T194 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| S196 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S219 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S221 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T222 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
| S225 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 25813380 | ||
| T227 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| S228 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| K229 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N241 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19349973, ... | ||
| K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N266 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| N283 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N288 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| C291 | Methylation | score1 | IEDB | 31844290 | ||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K467 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K468 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S471 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y473 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S475 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S478 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T479 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T486 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y493 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y528 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y531 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S583 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K143 | N143 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| C291 | Y291 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| K310 | R310 | Biomuta | DOID:263 / kidney cancer [ cosmic ] |
DAG View