Protein Information

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UniProt AC / UniProt ID Q13428 / TCOF_HUMAN
Protein Name Treacle protein
Gene Name Name: TCOF1
Organism Homo sapiens (Human)

PRO ID PR:Q13428
DAG View
PRO Name treacle protein (human)
Definition A treacle protein that is encoded in the genome of human.
Short Label hTCOF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13428 (TCOF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y15 Phosphorylation PhosphoSitePlus
K74 Acetylation PhosphoSitePlus
S83 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
T84 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S85 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S87 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S88 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
T102 Phosphorylation PhosphoSitePlus
S107 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T108 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
K124 Methylation PhosphoSitePlus
K126 Acetylation PhosphoSitePlus
S138 Phosphorylation phospho.ELM 17287340
T144 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K146 Acetylation PhosphoSitePlus
T147 O-Glycosylation GlyGen 23301498, 27655845, 29351928, ...28510447, 32119511
T147 Phosphorylation PhosphoSitePlus
S153 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
K155 Acetylation PhosphoSitePlus   UniProt 19608861
S156 Phosphorylation P06493 (CDK1) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18234856, ...18669648, 19690332, 20068231
S160 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S164 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T168 Phosphorylation PhosphoSitePlus
S171 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
T173 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
T210 Phosphorylation P68400 (CSNK2A1) IntAct   PhosphoSitePlus   Signor 25064736
S227 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
K244 Acetylation PhosphoSitePlus
T249 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...19690332, 20068231
S270 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
K296 Acetylation PhosphoSitePlus   UniProt 19608861
S304 Phosphorylation PhosphoSitePlus
T310 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T316 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K322 Acetylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S381 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 24275569, 17287340, 19690332, 20068231, 17924679
K393 Acetylation PhosphoSitePlus
T394 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S410 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S446 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...18669648, 20068231, 17924679
K449 Methylation PhosphoSitePlus
S475 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S477 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S478 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S479 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S482 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S484 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S503 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
K507 Acetylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
T533 O-Glycosylation GlyGen 23301498, 27655845, 29351928, ...28510447, 32119511
T533 Phosphorylation PhosphoSitePlus   UniProt 23186163
S549 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
K579 Acetylation PhosphoSitePlus
T581 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S582 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus 18669648, 18847512
S583 Phosphorylation P24941 (CDK2) , P06493 (CDK1) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18847512, ...18234856, 18669648, 17287340, 19690332, 20068231
K591 Ubiquitination PhosphoSitePlus
K600 Acetylation PhosphoSitePlus   UniProt 19608861
K600 Sumoylation PhosphoSitePlus
S608 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S610 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S611 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S614 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S615 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S617 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S620 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983
T663 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
K732 Acetylation PhosphoSitePlus
K732 Methylation PhosphoSitePlus
K732 Sumoylation PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
K746 Acetylation PhosphoSitePlus
K755 Acetylation PhosphoSitePlus   UniProt 19608861
K755 Sumoylation PhosphoSitePlus
S762 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S764 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340
S765 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S769 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S771 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S777 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S784 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S801 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
T805 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K811 Acetylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
S823 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S825 Phosphorylation phospho.ELM 17081983
T838 Phosphorylation PhosphoSitePlus
S846 Phosphorylation PhosphoSitePlus
S849 Phosphorylation PhosphoSitePlus
S868 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S870 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S871 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S875 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S877 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S890 Phosphorylation phospho.ELM 18669648, 15302935
K904 Acetylation PhosphoSitePlus
S906 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18220336, 18669648, 17287340, 20068231, 17924679
T914 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231, 17924679
S932 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S934 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S935 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S936 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S939 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S941 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S967 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18220336
T974 Phosphorylation PhosphoSitePlus
S982 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T983 Phosphorylation P24941 (CDK2) , P06493 (CDK1) phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 18847512, ...18234856, 19690332
S990 Phosphorylation phospho.ELM 17081983
S992 Phosphorylation phospho.ELM 18669648, 17081983
T993 Phosphorylation phospho.ELM 18669648, 17081983
S996 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S997 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S998 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S999 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
S1001 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
C1012 S-Nitrosylation dbSNO 26338901
T1026 Phosphorylation PhosphoSitePlus
S1036 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
T1060 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus
T1073 Phosphorylation PhosphoSitePlus
K1078 Acetylation PhosphoSitePlus
T1094 Phosphorylation PhosphoSitePlus
T1110 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1111 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 16964243, ...19690332
S1114 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1115 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1142 Phosphorylation PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus
S1168 Phosphorylation PhosphoSitePlus
T1171 Phosphorylation PhosphoSitePlus
T1175 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1179 Phosphorylation phospho.ELM 18669648
T1181 Phosphorylation phospho.ELM 18669648
T1186 Phosphorylation phospho.ELM 18669648
S1190 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1191 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1199 Phosphorylation PhosphoSitePlus
S1204 Phosphorylation PhosphoSitePlus
Y1206 Phosphorylation PhosphoSitePlus
T1208 Phosphorylation PhosphoSitePlus
T1222 Phosphorylation PhosphoSitePlus
S1227 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1228 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 18669648, 24275569, 19690332
S1230 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1232 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus
T1234 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1257 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...24275569, 17287340, 20068231
T1260 Phosphorylation PhosphoSitePlus
K1263 Acetylation PhosphoSitePlus
T1269 Phosphorylation PhosphoSitePlus
T1270 Phosphorylation PhosphoSitePlus
S1287 Phosphorylation PhosphoSitePlus
T1288 Phosphorylation PhosphoSitePlus
T1296 Phosphorylation PhosphoSitePlus
K1335 Ubiquitination PhosphoSitePlus
K1346 Acetylation PhosphoSitePlus
K1346 Ubiquitination PhosphoSitePlus
S1350 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17287340, ...17081983, 18669648, 24275569, 23186163, 20068231
T1358 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 17287340
S1361 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K1362 Acetylation PhosphoSitePlus
S1376 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 15302935, ...18669648, 23186163, 19690332
S1378 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 16964243, ...15302935, 18669648, 23186163, 19690332, 20068231, 17081983
T1382 Phosphorylation PhosphoSitePlus
T1385 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
K1403 Acetylation PhosphoSitePlus
K1405 Acetylation PhosphoSitePlus
S1407 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1410 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17525332, ...20068231
K1414 Acetylation PhosphoSitePlus   UniProt 19608861
K1414 Sumoylation PhosphoSitePlus
S1434 Phosphorylation PhosphoSitePlus
S1471 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1473 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S83 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
T84 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S85 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S87 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S88 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S107 Phosphorylation HPRD 18669648, 20068231
T108 Phosphorylation HPRD 20068231
S110 Phosphorylation HPRD 20068231
T144 Phosphorylation HPRD 17287340
T147 Phosphorylation HPRD 20068231
S153 Phosphorylation HPRD 17322306, 18767875, 18669648, ...20068231
S156 Phosphorylation HPRD 19664995, 17322306, 18212344, ...18767875, 19691289, 18452278, 19651622, 18669648, 19415658, 20068231, 17924679
S164 Phosphorylation HPRD 17081983, 20068231
T167 Phosphorylation HPRD 20068231
T168 Phosphorylation HPRD 19413330
S171 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231, 18452278
T173 Phosphorylation HPRD 19413330, 15345747, 20068231, ...18452278
S178 Phosphorylation HPRD 19413330, 18452278
S227 Phosphorylation HPRD 17924679
T233 Phosphorylation HPRD 19413330, 18669648, 20068231, ...17924679
T239 Phosphorylation HPRD 19413330, 18669648, 17924679
S298 Phosphorylation HPRD 17081983, 20068230, 18707149, ...19664995, 19007248
S304 Phosphorylation HPRD 19413330, 18491316, 17287340, ...18212344, 19562805, 18767875, 19664995, 19007248, 17322306, 18669648, 20166139, 18452278, 17924679, 19415658, 19691289
T317 Phosphorylation HPRD 17287340
S333 Phosphorylation HPRD 19651622
S335 Phosphorylation HPRD 19651622
S336 Phosphorylation HPRD 19651622
S337 Phosphorylation HPRD 19651622
S340 Phosphorylation HPRD 19651622
S342 Phosphorylation HPRD 19651622
S369 Phosphorylation HPRD 18669648, 17287340, 17924679
S398 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S400 Phosphorylation HPRD 19651622, 17081983, 20068231
S401 Phosphorylation HPRD 19651622, 17081983, 20068231
S402 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S405 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S407 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S426 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S433 Phosphorylation HPRD 20068231
T456 Phosphorylation HPRD 17322306, 19413330, 19664994, ...19664995, 20068231
S472 Phosphorylation HPRD 18452278
S478 Phosphorylation HPRD 18452278
S479 Phosphorylation HPRD 18452278
T504 Phosphorylation HPRD 17322306, 19651622, 18669648, ...19664995, 20068231
S505 Phosphorylation HPRD 17081983, 19664995, 19651622, ...18669648, 20068231, 17924679
S506 Phosphorylation HPRD 17322306, 17287340, 18767875, ...19664995, 18452278, 19651622, 18669648, 20068231, 17924679
S531 Phosphorylation HPRD 17081983
S533 Phosphorylation HPRD 17081983
S534 Phosphorylation HPRD 17081983, 18452278
S537 Phosphorylation HPRD 17081983, 18452278
S538 Phosphorylation HPRD 17081983, 18452278
S540 Phosphorylation HPRD 17081983
S543 Phosphorylation HPRD 17081983, 18452278
T586 Phosphorylation HPRD 18212344
T594 Phosphorylation HPRD 20068231
T596 Phosphorylation HPRD 20068231
S597 Phosphorylation HPRD 19691289
S601 Phosphorylation HPRD 20068231
T609 Phosphorylation HPRD 17081983
S616 Phosphorylation HPRD 17081983
S617 Phosphorylation HPRD 17081983, 20068231
S618 Phosphorylation HPRD 17081983
S619 Phosphorylation HPRD 17081983, 20068231
S622 Phosphorylation HPRD 17081983, 20068231
S624 Phosphorylation HPRD 18452278
S685 Phosphorylation HPRD 19651622, 18669648, 18452278
S687 Phosphorylation HPRD 19651622, 18669648, 17287340, ...18452278
S688 Phosphorylation HPRD 19651622, 18669648, 18452278
S692 Phosphorylation HPRD 19651622, 18669648, 18452278
S694 Phosphorylation HPRD 19651622, 18669648, 18452278
S700 Phosphorylation HPRD 19651622, 18669648, 18452278
S707 Phosphorylation HPRD 17287340
S724 Phosphorylation HPRD 17287340
T728 Phosphorylation HPRD 17287340
T779 Phosphorylation HPRD 17081983
T785 Phosphorylation HPRD 17081983
S791 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S793 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S794 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S798 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S800 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T806 Phosphorylation HPRD 17081983
S813 Phosphorylation HPRD 18669648, 17081983
S829 Phosphorylation HPRD 19664995, 18691976, 17287340, ...18212344, 18767875, 19691289, 19007248, 19651622, 17322306, 18669648, 18452278, 17924679, 19415658, 20068231, 20068230
T837 Phosphorylation HPRD 19691289, 19007248, 19664995, ...17924679, 20068231, 20068230
S855 Phosphorylation HPRD 17081983, 20068231
S857 Phosphorylation HPRD 17081983, 20068231
S858 Phosphorylation HPRD 17081983, 20068231
S859 Phosphorylation HPRD 17081983, 20068231, 18452278
S862 Phosphorylation HPRD 17081983, 20068231, 18452278
S864 Phosphorylation HPRD 17081983, 20068231, 18452278
T873 Phosphorylation HPRD 20068231
S890 Phosphorylation HPRD 15302935, 19664994, 19691289, ...18452278
T897 Phosphorylation HPRD 19691289
S905 Phosphorylation HPRD 20068231
T906 Phosphorylation HPRD 19413330, 19664995, 20068231
S913 Phosphorylation HPRD 17081983, 20068231
S915 Phosphorylation HPRD 18669648, 17081983, 20068231
T916 Phosphorylation HPRD 18669648, 17081983, 20068231
S919 Phosphorylation HPRD 18669648, 17081983, 20068231
S920 Phosphorylation HPRD 18669648, 17081983
S921 Phosphorylation HPRD 18669648, 17081983, 20068231
S922 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S924 Phosphorylation HPRD 18669648, 17081983
T933 Phosphorylation HPRD 17081983
T937 Phosphorylation HPRD 17081983, 20068231
T996 Phosphorylation HPRD 18212344
T1033 Phosphorylation HPRD 18669648, 18491316, 19664995, ...20068231
S1034 Phosphorylation HPRD 19413330, 16964243, 15302935, ...19664995, 19691289, 18669648, 20068231
S1037 Phosphorylation HPRD 18669648
T1038 Phosphorylation HPRD 18491316
S1039 Phosphorylation HPRD 18669648
T1102 Phosphorylation HPRD 18669648
T1104 Phosphorylation HPRD 18669648
T1109 Phosphorylation HPRD 18669648
S1113 Phosphorylation HPRD 18669648, 17081983, 18452278
S1114 Phosphorylation HPRD 18669648, 18452278
S1124 Phosphorylation HPRD 17081983
T1145 Phosphorylation HPRD 19413330, 20068231
S1150 Phosphorylation HPRD 19413330, 18691976, 17081983, ...20058876, 19664995, 18452278, 19651622, 18669648, 19415658, 20068231
S1151 Phosphorylation HPRD 19413330, 17322306, 18491316, ...20058876, 16964243, 18212344, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 18707149, 18452278, 19415658, 20068231, 20068230
S1153 Phosphorylation HPRD 19413330, 18669648, 17081983
T1157 Phosphorylation HPRD 18669648
S1180 Phosphorylation HPRD 19413330, 17287340, 17081983, ...19664994, 19651622, 18669648, 20068231
T1193 Phosphorylation HPRD 20068231
S1273 Phosphorylation HPRD 19664995, 18691976, 17287340, ...18212344, 18767875, 19691289, 19007248, 19651622, 17322306, 18669648, 18707149, 20166139, 18452278, 19415658, 20068231, 17924679
T1281 Phosphorylation HPRD 18669648, 17287340, 20068231
S1284 Phosphorylation HPRD 17287340
S1299 Phosphorylation HPRD 19413330, 17287340, 18767875, ...15302935, 19664995, 18452278, 19651622, 18669648, 20068231
S1301 Phosphorylation HPRD 19413330, 18691976, 18491316, ...17287340, 16964243, 18212344, 18767875, 19664994, 19007248, 18452278, 17322306, 18669648, 19651622, 19664995, 20058876, 20068230, 19415658, 20068231, 19691289
T1305 Phosphorylation HPRD 18452278
S1309 Phosphorylation HPRD 19415658, 20068231
S1330 Phosphorylation HPRD 19651622, 18669648, 20068231
S1333 Phosphorylation HPRD 18077418, 17525332, 18669648, ...20068231, 18452278
S1357 Phosphorylation HPRD 18691976
S1394 Phosphorylation HPRD 15302935
S1396 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S1168 Phosphorylation PhosphoSitePlus
T1176 Phosphorylation PhosphoSitePlus
S1178 Phosphorylation PhosphoSitePlus
T1182 Phosphorylation PhosphoSitePlus
T1187 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T974 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
S1003 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S83 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
T84 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S85 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S87 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S88 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S107 Phosphorylation HPRD 18669648, 20068231
T108 Phosphorylation HPRD 20068231
S110 Phosphorylation HPRD 20068231
T144 Phosphorylation HPRD 17287340
T147 Phosphorylation HPRD 20068231
S153 Phosphorylation HPRD 17322306, 18767875, 18669648, ...20068231
S156 Phosphorylation HPRD 19664995, 17322306, 18212344, ...18767875, 19691289, 18452278, 19651622, 18669648, 19415658, 20068231, 17924679
S164 Phosphorylation HPRD 17081983, 20068231
T167 Phosphorylation HPRD 20068231
T168 Phosphorylation HPRD 19413330
S171 Phosphorylation HPRD 19413330, 19651622, 17081983, ...20068231, 18452278
T173 Phosphorylation HPRD 19413330, 15345747, 20068231, ...18452278
S178 Phosphorylation HPRD 19413330, 18452278
S198 Phosphorylation HPRD 17081983
S200 Phosphorylation HPRD 17081983
T203 Phosphorylation HPRD 17081983
S204 Phosphorylation HPRD 17081983
S205 Phosphorylation HPRD 17081983
S206 Phosphorylation HPRD 17081983
S207 Phosphorylation HPRD 17081983
T210 Phosphorylation HPRD 17081983
T230 Phosphorylation HPRD 20068231
S233 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19664995
T249 Phosphorylation HPRD 19413330, 18669648, 19664994, ...19664995, 20068231
S304 Phosphorylation HPRD 17924679
T310 Phosphorylation HPRD 19413330, 18669648, 20068231, ...17924679
T316 Phosphorylation HPRD 19413330, 18669648, 17924679
S375 Phosphorylation HPRD 17081983, 20068230, 18707149, ...19664995, 19007248
S381 Phosphorylation HPRD 19413330, 18491316, 17287340, ...18212344, 19562805, 18767875, 19664995, 19007248, 17322306, 18669648, 20166139, 18452278, 17924679, 19415658, 19691289
T394 Phosphorylation HPRD 17287340
S410 Phosphorylation HPRD 19651622
S412 Phosphorylation HPRD 19651622
S413 Phosphorylation HPRD 19651622
S414 Phosphorylation HPRD 19651622
S417 Phosphorylation HPRD 19651622
S419 Phosphorylation HPRD 19651622
S446 Phosphorylation HPRD 18669648, 17287340, 17924679
S475 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S477 Phosphorylation HPRD 19651622, 17081983, 20068231
S478 Phosphorylation HPRD 19651622, 17081983, 20068231
S479 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S482 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S484 Phosphorylation HPRD 19651622, 17081983, 20068231, ...18452278
S503 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S510 Phosphorylation HPRD 20068231
T533 Phosphorylation HPRD 17322306, 19413330, 19664994, ...19664995, 20068231
S549 Phosphorylation HPRD 18452278
S555 Phosphorylation HPRD 18452278
S556 Phosphorylation HPRD 18452278
T581 Phosphorylation HPRD 17322306, 19651622, 18669648, ...19664995, 20068231
S582 Phosphorylation HPRD 17081983, 19664995, 19651622, ...18669648, 20068231, 17924679
S583 Phosphorylation HPRD 17322306, 17287340, 18767875, ...19664995, 18452278, 19651622, 18669648, 20068231, 17924679
S608 Phosphorylation HPRD 17081983
S610 Phosphorylation HPRD 17081983
S611 Phosphorylation HPRD 17081983, 18452278
S614 Phosphorylation HPRD 17081983, 18452278
S615 Phosphorylation HPRD 17081983, 18452278
S617 Phosphorylation HPRD 17081983
S620 Phosphorylation HPRD 17081983, 18452278
T663 Phosphorylation HPRD 18212344
T671 Phosphorylation HPRD 20068231
T673 Phosphorylation HPRD 20068231
S674 Phosphorylation HPRD 19691289
S678 Phosphorylation HPRD 20068231
T686 Phosphorylation HPRD 17081983
S693 Phosphorylation HPRD 17081983
S694 Phosphorylation HPRD 17081983, 20068231
S695 Phosphorylation HPRD 17081983
S696 Phosphorylation HPRD 17081983, 20068231
S699 Phosphorylation HPRD 17081983, 20068231
S701 Phosphorylation HPRD 18452278
S762 Phosphorylation HPRD 19651622, 18669648, 18452278
S764 Phosphorylation HPRD 19651622, 18669648, 17287340, ...18452278
S765 Phosphorylation HPRD 19651622, 18669648, 18452278
S769 Phosphorylation HPRD 19651622, 18669648, 18452278
S771 Phosphorylation HPRD 19651622, 18669648, 18452278
S777 Phosphorylation HPRD 19651622, 18669648, 18452278
S784 Phosphorylation HPRD 17287340
S801 Phosphorylation HPRD 17287340
T805 Phosphorylation HPRD 17287340
T856 Phosphorylation HPRD 17081983
T862 Phosphorylation HPRD 17081983
S868 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S870 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S871 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S875 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
S877 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
T883 Phosphorylation HPRD 17081983
S890 Phosphorylation HPRD 18669648, 17081983
S906 Phosphorylation HPRD 19664995, 18691976, 17287340, ...18212344, 18767875, 19691289, 19007248, 19651622, 17322306, 18669648, 18452278, 17924679, 19415658, 20068231, 20068230
T914 Phosphorylation HPRD 19691289, 19007248, 19664995, ...17924679, 20068231, 20068230
Site PTM Type PTM Enzyme Score Source PMID
S868 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
S875 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
T983 Phosphorylation PhosphoSitePlus
S1050 Phosphorylation PhosphoSitePlus
T1072 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus
S1076 Phosphorylation PhosphoSitePlus
T1077 Phosphorylation PhosphoSitePlus
S1078 Phosphorylation PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
T1320 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q13428 (TCOF1) T210 O60934 (NBN) unknown eFIP 25064736


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S88 L88 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S110 Y110 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K122 Q122 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T147 M147 Biomuta DOID:1324 / lung cancer [ tcga ]
T147 S147 Biomuta DOID:1324 / lung cancer [ tcga ]
T168 M168 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S273 I273 Biomuta DOID:3571 / liver cancer [ icgc ]
S277 Y277 Biomuta DOID:363 / uterine cancer [ tcga ]
S328 F328 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S343 R343 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S365 L365 Biomuta DOID:4362 / cervical cancer [ tcga ]
S381 F381 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S475 * Biomuta DOID:363 / uterine cancer [ tcga ]
S477 I477 Biomuta DOID:3571 / liver cancer [ icgc ]
S479 N479 Biomuta DOID:363 / uterine cancer [ tcga ]
S484 R484 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S615 L615 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S620 N620 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T663 A663 Biomuta DOID:1909 / melanoma [ cosmic ]
S674 F674 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S765 I765 Biomuta DOID:3571 / liver cancer [ icgc ]
S771 N771 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S823 F823 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S875 L875 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S877 I877 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T974 I974 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T983 A983 Biomuta DOID:1324 / lung cancer [ tcga ]
S990 L990 Biomuta DOID:1909 / melanoma [ tcga ]
C1012 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
C1012 F1012 Biomuta DOID:3571 / liver cancer [ icgc ]
S1036 I1036 Biomuta DOID:263 / kidney cancer [ tcga ]
S1142 I1142 Biomuta DOID:3571 / liver cancer [ icgc ]
T1179 A1179 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
Y1206 D1206 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1227 C1227 Biomuta DOID:263 / kidney cancer [ icgc, tcga ]
S1227 F1227 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1228 I1228 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S1232 F1232 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:1324 / lung cancer [ tcga ]
S1287 * Biomuta DOID:11934 / head and neck cancer [ tcga ]
K1335 R1335 Biomuta DOID:263 / kidney cancer [ icgc ]
K1403 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S1407 F1407 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K1414 T1414 Biomuta DOID:1612 / breast cancer [ cosmic ]