iPTMnet Report for Q13404 (UBE2V1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13404 / UB2V1_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 variant 1
Gene Name Name: UBE2V1
Synonyms:CROC1,UBE2V,UEV1;ORFNames:P/OKcl.19;
Organism Homo sapiens (Human)

PRO ID PR:Q13404
DAG View
PRO Name ubiquitin-conjugating enzyme E2 variant 1 (human)
Definition A ubiquitin-conjugating enzyme E2 variant 1 that is encoded in the genome of human.
Short Label hUBE2V1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13404 (UBE2V1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 25944712
S7 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
R63 Methylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K74 Acetylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
R125 Methylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T86 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T42 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
T109 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R63 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R63 Q63 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R125 W125 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]