iPTMnet Report for Q13352 (ITGB3BP)
Protein Information
| UniProt AC / UniProt ID | Q13352 / CENPR_HUMAN |
| Protein Name | Centromere protein R |
| Gene Name | Name: ITGB3BP Synonyms:CENPR,NRIF3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13352 |
| PRO Name | centromere protein R (human) |
| Definition | A centromere protein R that is encoded in the genome of human. |
| Short Label | hITGB3BP |
| Category | organism-gene |
DAG ViewQ13352 (ITGB3BP) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K8 | Sumoylation | score1 | PhosphoSitePlus | |||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
| K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S28 | Phosphorylation | Q13153 (PAK1) | score4 | PhosphoSitePlus RLIMS-P Signor UniProt | 11713274, 18521086 | |
| Y32 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S33 | Phosphorylation | P24941 (CDK2) | score3 | neXtProt PhosphoSitePlus | 11810239 | |
| S46 | Phosphorylation | P24941 (CDK2) | score3 | neXtProt PhosphoSitePlus | 11810239 | |
| S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K66 | Sumoylation | score1 | PhosphoSitePlus | |||
| K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S71 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
| T73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K76 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K92 | Sumoylation | score1 | PhosphoSitePlus | |||
| C127 | Methylation | score1 | IEDB | 31844290 | ||
| K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S168 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S17 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 19691289, ... | ||
| S71 | Phosphorylation | score0 | HPRD | 18691976, 20068231 | ||
| S126 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S168 | Phosphorylation | score0 | HPRD | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K27 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S6 | T6 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K22 | N22 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S28 | N28 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S33 | T33 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S60 | P60 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
| K154 | N154 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S168 | I168 | Biomuta | DOID:3953 / adrenal gland cancer [ cosmic ] |
