Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13347 / EIF3I_HUMAN
Protein Name Eukaryotic translation initiation factor 3 subunit I
Gene Name Name: EIF3I
Synonyms:EIF3S2;
Organism Homo sapiens (Human)

PRO ID PR:Q13347
DAG View
PRO Name eukaryotic translation initiation factor 3 subunit I (human)
Definition A eukaryotic translation initiation factor 3 subunit I that is encoded in the genome of human.
Short Label hEIF3I
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13347 (EIF3I) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Sumoylation PhosphoSitePlus
K2 Ubiquitination PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
R77 Methylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
C144 S-Nitrosylation dbSNO 19483679
K148 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K185 Sumoylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
S207 Phosphorylation HPRD 20068231
K208 Ubiquitination PhosphoSitePlus
K213 Sumoylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus   UniProt 23186163
K224 Ubiquitination PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
K264 Acetylation PhosphoSitePlus   UniProt 19608861
K264 Ubiquitination PhosphoSitePlus
K282 Sumoylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
Y308 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455, 18083107


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S75 N75 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R77 P77 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
R77 S77 Biomuta DOID:1612 / breast cancer [ tcga ]
R77 H77 Biomuta DOID:363 / uterine cancer [ tcga ]
K141 R141 Biomuta DOID:363 / uterine cancer [ tcga ]
T219 A219 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y241 C241 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K282 N282 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S302 G302 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]