iPTMnet Report for Q13330 (MTA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13330 / MTA1_HUMAN
Protein Name Metastasis-associated protein MTA1
Gene Name Name: MTA1
Organism Homo sapiens (Human)

PRO ID PR:Q13330
DAG View
PRO Name metastasis-associated protein MTA1 (human)
Definition A metastasis-associated protein MTA1 that is encoded in the genome of human.
Short Label hMTA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13330 (MTA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y11 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
C44 Methylation IEDB 31844290
K98 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus   UniProt 19805145
K208 Ubiquitination PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
R234 Methylation PhosphoSitePlus
S237 O-Glycosylation GlyGen 29485866, 34019948, 34725712, ...28657654
S241 O-Glycosylation GlyGen 29485866, 34019948, 34725712, ...28657654
S241 Phosphorylation PhosphoSitePlus
S246 O-Glycosylation GlyGen 29485866, 34019948, 34725712, ...28657654
K305 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y355 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
S386 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 18669648, 19690332, 20068231
Y427 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S449 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18669648, 20068231
S458 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
T467 Phosphorylation phospho.ELM 17081983
K509 Sumoylation PRO   PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S522 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18847512, ...18669648, 19690332, 20068231
K527 Ubiquitination PhosphoSitePlus
K532 Methylation PhosphoSitePlus
S555 O-Glycosylation GlyGen 29485866, 34019948, 34725712, ...28657654
S562 Phosphorylation PhosphoSitePlus
T564 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18220336, ...18669648, 32387766, 19690332
S576 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 19690332, 20068231
T578 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...19690332, 20068231
K582 Methylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
S584 Phosphorylation PhosphoSitePlus
R604 Methylation PhosphoSitePlus
K626 Acetylation PhosphoSitePlus   UniProt 16617102, 19805145, 17671180
K626 Ubiquitination UniProt 19805145
R636 Methylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y659 Phosphorylation PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
T677 Phosphorylation PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
Y685 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S386 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19664995, 19691289, 18669648, 20068231
S446 Phosphorylation HPRD 19651622, 17081983, 20068231, ...19691289
S449 Phosphorylation HPRD 19651622, 20166139, 18669648, ...19691289, 20068231
T467 Phosphorylation HPRD 17081983
S520 Phosphorylation HPRD 19413330, 19415658, 20068231, ...19664995
S522 Phosphorylation HPRD 19413330, 18691976, 19691289, ...19664995, 18669648, 19415658, 20068231
S561 Phosphorylation HPRD 20068231
S562 Phosphorylation HPRD 20068231
T564 Phosphorylation HPRD 19413330, 16964243, 19664994, ...19664995, 18669648, 20068231
S576 Phosphorylation HPRD 19413330, 15302935, 19664994, ...19664995, 19651622, 18669648, 20068231
T578 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19664995, 17322306, 18669648, 20068231
K626 Acetylation PR:000007102 (EP300) PRO 16617102
Site PTM Type PTM Enzyme Score Source PMID
K61 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048463 (hMTA1/Sumo:1) suK509 PRO
PR:000028587 (hMTA1/iso:1/Ac:1) acK626 PR:000007102 (EP300) PRO 16617102


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S230 N230 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R234 Q234 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y355 C355 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S520 F520 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S562 I562 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T564 M564 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ icgc ]
S673 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S675 L675 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K678 N678 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]