iPTMnet Report for Q13303 (KCNAB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13303 / KCAB2_HUMAN
Protein Name Voltage-gated potassium channel subunit beta-2
Gene Name Name: KCNAB2
Synonyms:KCNA2B,KCNK2;
Organism Homo sapiens (Human)

PRO ID PR:Q13303
DAG View
PRO Name voltage-gated potassium channel subunit beta-2 (human)
Definition A voltage-gated potassium channel subunit beta-2 that is encoded in the genome of human.
Short Label hKCNAB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13303 (KCNAB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y2 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
T6 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21357749, 23186163, 19690332
R12 Methylation PhosphoSitePlus
S14 O-Glycosylation GlyGen 31492838
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
T18 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus   RLIMS-P 21357749
Y25 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S26 O-Glycosylation GlyGen 31492838
S26 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
R28 Methylation PhosphoSitePlus   UniProt 24129315
S31 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21357749
K44 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 21357749
K124 Acetylation PhosphoSitePlus   UniProt 19608861
K124 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
Y184 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S266 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 12604245
K268 Ubiquitination PhosphoSitePlus
K274 Acetylation PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K276 Acetylation PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
K362 Acetylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y25 Phosphorylation HPRD 15592455, 19901323
Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
T18 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
Y25 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q13303 (KCNAB2) S9 Q15691 (MAPRE1) unknown eFIP 21357749


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T6 M6 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R12 Q12 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S14 L14 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T18 M18 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S20 A20 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S20 F20 Biomuta DOID:4159 / skin cancer [ cosmic ]
S31 C31 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S206 F206 Biomuta DOID:4159 / skin cancer [ cosmic ]