iPTMnet Report Q13286 CLN3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q13286 / CLN3_HUMAN
Protein Name	Battenin precursor
Gene Name	Name: CLN3 Synonyms:BTS;
Organism	Homo sapiens (Human)

PRO ID	PR:Q13286 DAG View
PRO Name	battenin (human)
Definition	A battenin that is encoded in the genome of human.
Short Label	hCLN3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q13286 (CLN3) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S12	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	21406692, 23186163, 15302935, ...18669648, 19690332, 20068231
	S14	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	21406692, 23186163, 15302935, ...18669648, 19690332, 20068231
	T19	Phosphorylation		score1	PhosphoSitePlus
	N71	N-Glycosylation		score4	GlyGen UniProt	17286803, 24190977
	T80	O-Glycosylation		score2	GlyGen PhosphoSitePlus	25813380
	N85	N-Glycosylation		score4	GlyGen UniProt	17286803, 24190977
	S125	Phosphorylation		score1	PhosphoSitePlus
	K262	Ubiquitination		score1	PhosphoSitePlus
	S267	Phosphorylation		score1	PhosphoSitePlus
	S268	Phosphorylation		score1	PhosphoSitePlus
	T276	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S12	Phosphorylation		score0	HPRD	18691976, 17081983, 15302935, ...18452278, 19651622, 18669648, 18707149, 20166139, 20068231
	S14	Phosphorylation		score0	HPRD	18578522, 17081983, 15302935, ...19651622, 18669648, 20166139, 20068231
	T19	Phosphorylation		score0	HPRD	20068231

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T80	Phosphorylation		score1	PhosphoSitePlus
	S87	Phosphorylation		score1	PhosphoSitePlus
	S94	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S12	L12	Biomuta		DOID:10534 / stomach cancer [ cosmic ]
S14	Y14	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T19	I19	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T80	M80	Biomuta		[ cosmic, cosmic ] DOID:1612 / breast cancer [ cosmic, icgc, cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ]
S94	Y94	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
S125	I125	Biomuta		DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
S267	F267	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]