Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13283 / G3BP1_HUMAN
Protein Name Ras GTPase-activating protein-binding protein 1
Gene Name Name: G3BP1
Synonyms:G3BP;
Organism Homo sapiens (Human)

PRO ID PR:Q13283
DAG View
PRO Name Ras GTPase-activating protein-binding protein 1 (human)
Definition A Ras GTPase-activating protein-binding protein 1 that is encoded in the genome of human.
Short Label hG3BP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13283 (G3BP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Methylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
Y20 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
Y56 Phosphorylation P06239 (LCK) PhosphoSitePlus 15743820
K59 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
K76 Acetylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
T143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S149 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 22205990, 27920254, 17693683, ...31171631, 21406692, 31171633, 23186163, 11604510, 18220336, 12642610, 18318008, 24275569, 23163895, 30135423, 27022092, 17081983, 15302935, 18691976, 18669648, 24324649, 20068231
T162 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
S230 Phosphorylation phospho.ELM   PhosphoSitePlus 15659558, 18669648, 17287340
S231 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935, 15659558, 17287340
S232 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 15659558, 17081983, ...11604510, 18220336, 15302935, 16094384, 12642610, 15144186, 18669648, 24275569, 17287340, 19690332, 20068231
T241 Phosphorylation PhosphoSitePlus
R247 Methylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus   UniProt 23186163
S253 Phosphorylation PhosphoSitePlus   UniProt 23186163
K287 Ubiquitination PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
S373 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K376 Acetylation PhosphoSitePlus   UniProt 19608861
K376 Ubiquitination PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
R403 Methylation PhosphoSitePlus
R427 Methylation PhosphoSitePlus
R429 Methylation PhosphoSitePlus   UniProt 24129315
R435 Methylation PhosphoSitePlus   UniProt 24129315
R443 Methylation PhosphoSitePlus
R447 Methylation PhosphoSitePlus   UniProt 24129315
K453 Methylation PhosphoSitePlus
R460 Methylation PhosphoSitePlus   UniProt 24129315
R465 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
Y56 Phosphorylation HPRD 15743820
Y133 Phosphorylation HPRD 17081983, 18452278
T143 Phosphorylation HPRD 17322306, 18669648, 20058876, ...18452278
S149 Phosphorylation HPRD 19413330, 18691976, 18491316, ...11604510, 20230923, 19664994, 20058876, 19664995, 18452278, 19651622, 18669648, 17693683, 20166139, 12642610, 19415658, 20068231
T162 Phosphorylation HPRD 20068231
Y174 Phosphorylation HPRD 17081983
S230 Phosphorylation HPRD 18691976, 18491316, 17287340, ...20230923, 19664995, 15144186, 18452278, 19651622, 18669648, 20166139, 20068231
S231 Phosphorylation HPRD 19413330, 18491316, 17287340, ...20230923, 19664995, 15144186, 18452278, 19651622, 20068231
S232 Phosphorylation HPRD 19413330, 18691976, 18578522, ...18491316, 17287340, 20230923, 18767875, 20058876, 19664995, 18452278, 17322306, 18669648, 19651622, 18707149, 20166139, 17924679, 19415658, 20068231, 20068230
T241 Phosphorylation HPRD 18212344
S373 Phosphorylation HPRD 18669648, 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q13283 (G3BP1) S149 P20936 (RASA1) unknown eFIP 22205990