iPTMnet Report for Q13263 (TRIM28)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13263 / TIF1B_HUMAN
Protein Name Transcription intermediary factor 1-beta
Gene Name Name: TRIM28
Synonyms:KAP1,RNF96,TIF1B;
Organism Homo sapiens (Human)

PRO ID PR:Q13263
DAG View
PRO Name transcription intermediary factor 1-beta (human)
Definition A transcription intermediary factor 1-beta that is encoded in the genome of human.
Short Label hTRIM28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13263 (TRIM28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692, 22223895, ...22814378, 20068231
S4 Phosphorylation PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S19 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...24275569, 20068231
S26 Phosphorylation PhosphoSitePlus   UniProt 23186163
K31 Acetylation PhosphoSitePlus
K31 Sumoylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S45 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S49 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 18220336
K127 Ubiquitination PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus   UniProt 23186163
K188 Acetylation PhosphoSitePlus
K188 Sumoylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K199 Sumoylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
K254 Sumoylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S258 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K261 Sumoylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K266 Acetylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
R282 Methylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K289 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K304 Acetylation PhosphoSitePlus   UniProt 19608861
K304 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K319 Sumoylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K337 Sumoylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K340 Acetylation PhosphoSitePlus   UniProt 19608861
K340 Ubiquitination PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K366 Acetylation PhosphoSitePlus
K366 Sumoylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
Y369 Phosphorylation PhosphoSitePlus
K377 Acetylation PhosphoSitePlus   UniProt 19608861
K377 Sumoylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K390 Sumoylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
T415 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...32522876, 31373491, 34019948, 35083852, 22967762, 32119511, 28510447, 33465208
S417 O-Glycosylation GlyGen 31373491
S417 Phosphorylation PhosphoSitePlus   UniProt 23186163
R427 Methylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
K434 Sumoylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
S437 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S439 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S440 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648
Y449 Phosphorylation PhosphoSitePlus   RLIMS-P 28869544, 23645696
Y449 Phosphorylation P07948 (LYN) PhosphoSitePlus 23645696
S453 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y458 Phosphorylation PhosphoSitePlus   RLIMS-P 28869544, 23645696
Y458 Phosphorylation P07948 (LYN) PhosphoSitePlus 23645696
S459 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S466 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
K469 Acetylation PhosphoSitePlus
K469 Sumoylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
S471 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 17287340, 30323812
S473 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...32522876, 31373491, 34019948, 35083852, 22967762, 32119511, 28510447, 33465208
S473 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 22715096, 16964243, 29955894, ...22496453, 18590578, 21406692, 22491012, 23186163, 35350437, 35533307, 34419074, 19690332, 28864417, 18220336, 23740979, 25846574, 28869544, 27364555, 16083285, 17287340, 17081983, 15302935, 22205726, 18669648, 21851590, 20068231, 26158765, 30323812
S473 Phosphorylation O14757 (CHEK1) PhosphoSitePlus   RLIMS-P+ 21851590, 22496453
S473 Phosphorylation O96017 (CHEK2) PhosphoSitePlus 22715096, 22491012
S473 Phosphorylation P49137 (MAPKAPK2) neXtProt   PhosphoSitePlus 23740979
S473 Phosphorylation Q05655 (PRKCD) Signor 18590578
S479 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S489 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T498 Phosphorylation PhosphoSitePlus   UniProt 23186163
S501 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 24275569, ...17287340, 19690332
K507 Sumoylation PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
T514 Phosphorylation PhosphoSitePlus
Y517 Phosphorylation PhosphoSitePlus   RLIMS-P 28869544, 23645696
Y517 Phosphorylation P07948 (LYN) PhosphoSitePlus 23645696
T531 Phosphorylation PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
T541 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 16964243, 24275569, ...23186163, 20068231
K554 Sumoylation PhosphoSitePlus
K575 Acetylation PhosphoSitePlus
K575 Sumoylation PhosphoSitePlus
K575 Ubiquitination PhosphoSitePlus
S594 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340, 19690332, ...24275569
S596 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S598 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T599 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S600 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S601 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T611 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S612 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
S624 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T626 Phosphorylation phospho.ELM 18669648
C669 Methylation IEDB 31844290
K676 Sumoylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S689 Phosphorylation PhosphoSitePlus   UniProt 24275569
K695 Ubiquitination PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus   UniProt 20068231
K750 Sumoylation PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
S752 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Y755 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S756 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S757 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
K770 Acetylation PhosphoSitePlus   UniProt 19608861
K770 Sumoylation PhosphoSitePlus
K770 Ubiquitination PhosphoSitePlus
K774 Acetylation PhosphoSitePlus   UniProt 19608861
K774 Sumoylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
K779 Acetylation PhosphoSitePlus
K779 Sumoylation PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus   UniProt 23186163
R790 Methylation PhosphoSitePlus
K804 Sumoylation PhosphoSitePlus
K804 Ubiquitination PhosphoSitePlus
S806 O-Glycosylation GlyGen 31373491
S816 Phosphorylation PhosphoSitePlus
S823 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S824 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P+   RLIMS-P   UniProt 24907272, 16862143, 19584288, ...17178852, 22496453, 23034801, 22732494, 17525332, 22491012, 25905708, 20515076, 18669648, 25846574, 23678292, 25173174, 21228624, 33514850, 23935532, 27588518, 32290532, 32133046, 17942393, 30206173, 23096706, 22205726, 20424263, 35350437, 32068487, 30323812, 35031618
S824 Phosphorylation Q13315 (ATM) neXtProt   PhosphoSitePlus   RLIMS-P+ 17942393, 16862143, 22491012, ...22205726, 23096706
S828 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18491316, 17081983, 20068231
S9 Phosphorylation HPRD 18491316, 19664995
S14 Phosphorylation HPRD 19413330, 20058876, 17081983
S17 Phosphorylation HPRD 19413330, 20058876, 17081983, ...20068231
S19 Phosphorylation HPRD 19413330, 18578522, 18491316, ...17081983, 19691289, 19007248, 19651622, 20068231
S26 Phosphorylation HPRD 19413330, 18578522
S49 Phosphorylation HPRD 17081983, 19664995, 18452278, ...18669648, 19415658, 20068231
S50 Phosphorylation HPRD 18491316, 17081983, 19664995, ...18452278, 18669648, 19415658, 17924679
S138 Phosphorylation HPRD 20068231
S258 Phosphorylation HPRD 18669648, 20068231
S437 Phosphorylation HPRD 18669648, 20068231
S439 Phosphorylation HPRD 18669648
S440 Phosphorylation HPRD 18077418, 17525332, 18669648
S466 Phosphorylation HPRD 17287340
S471 Phosphorylation HPRD 17287340, 18767875, 19664995, ...18452278, 19651622, 18669648, 20166139, 20068231
S473 Phosphorylation HPRD 19413330, 17322306, 18578522, ...17287340, 18212344, 16964243, 18767875, 19664994, 19691289, 19664995, 19651622, 18669648, 20058876, 18707149, 20166139, 18452278, 20068231, 17924679
S479 Phosphorylation HPRD 20068231
S489 Phosphorylation HPRD 18669648, 20068231, 18452278
T498 Phosphorylation HPRD 19651622, 20068231, 18452278
S501 Phosphorylation HPRD 17287340, 17525332, 19664994
T541 Phosphorylation HPRD 17322306, 17287340, 16964243, ...20068231
S594 Phosphorylation HPRD 19413330, 17287340, 17081983, ...19664995, 18452278, 18669648, 19007248, 20068231
S596 Phosphorylation HPRD 19413330, 18669648, 19007248, ...19664995, 17081983
S598 Phosphorylation HPRD 18669648, 18452278, 19664995, ...20068231, 17081983
T599 Phosphorylation HPRD 18669648, 17081983, 19664995
S600 Phosphorylation HPRD 19413330, 18669648, 17081983
S601 Phosphorylation HPRD 19413330, 18669648, 17081983, ...20068231, 19664995
T611 Phosphorylation HPRD 18669648, 20068231
S612 Phosphorylation HPRD 20068231
T620 Phosphorylation HPRD 20068231
S624 Phosphorylation HPRD 18669648, 20068231
T626 Phosphorylation HPRD 18669648, 20068231
S681 Phosphorylation HPRD 19651622, 17081983
S683 Phosphorylation HPRD 19413330, 19651622, 17081983
S689 Phosphorylation HPRD 19413330
S697 Phosphorylation HPRD 20068231
S752 Phosphorylation HPRD 18669648, 16964243, 20068231
Y755 Phosphorylation HPRD 18669648
S756 Phosphorylation HPRD 18669648, 20068231
S757 Phosphorylation HPRD 19413330, 18669648, 16964243, ...20068231, 19664995
S823 Phosphorylation HPRD 18669648, 17081983, 20068231
S824 Phosphorylation HPRD 18077418, 17525332, 18669648, ...20068231, 18452278
S828 Phosphorylation HPRD 17081983, 18452278


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q13263 (TRIM28) S473 P12004 (PCNA) unknown eFIP 29955894