Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13242 / SRSF9_HUMAN
Protein Name Serine/arginine-rich splicing factor 9
Gene Name Name: SRSF9
Synonyms:SFRS9,SRP30C;
Organism Homo sapiens (Human)

PRO ID PR:Q13242
DAG View
PRO Name serine/arginine-rich splicing factor 9 (human)
Definition A serine/arginine-rich splicing factor 9 that is encoded in the genome of human.
Short Label hSRSF9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13242 (SRSF9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
R8 Methylation PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
R63 Methylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
C80 S-Nitrosylation dbSNO 26338901
R88 Methylation PhosphoSitePlus
R93 Methylation PhosphoSitePlus
R98 Methylation PhosphoSitePlus
R101 Methylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
R132 Methylation PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
R154 Methylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
R163 Methylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
R171 Methylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
R181 Methylation PhosphoSitePlus
S187 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T188 Phosphorylation PhosphoSitePlus
S189 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 15302935, ...19651622, 18669648, 20068230, 20068231, 18212344
Y190 Phosphorylation HPRD   PhosphoSitePlus 17081983
Y192 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648
S193 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 20068231
R194 Methylation PhosphoSitePlus
S195 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S197 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S204 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18452278, ...19651622, 18707149, 20166139, 20068231, 18212344
Y206 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S208 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
R209 Methylation PhosphoSitePlus
S211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 16964243, 18707149, 18691976, ...21406692, 23186163, 18212344, 20230923, 18452278, 19367720, 24275569, 18220336, 18767875, 20058876, 19651622, 16083285, 17287340, 17081983, 19664995, 17322306, 18669648, 20166139, 17924679, 20068231, 20068230
Y214 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17016520, 17389395, 17081983, ...18220336, 24275569, 20068231
S216 Phosphorylation P24941 (CDK2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17287340, ...17081983, 18220336, 18847512, 20230923, 20058876, 19664995, 19651622, 18669648, 20166139, 23186163, 17924679, 18212344, 20068231, 16964243
Y221 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y17 * Biomuta DOID:3571 / liver cancer [ icgc ]
R88 G88 Biomuta DOID:1909 / melanoma [ tcga ]
R88 K88 Biomuta DOID:1909 / melanoma [ tcga ]
R93 W93 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K144 N144 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S178 F178 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S189 I189 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
Y192 * Biomuta DOID:1612 / breast cancer [ icgc ]
Y214 H214 Biomuta DOID:1324 / lung cancer [ tcga ]