iPTMnet Report for Q13206 (DDX10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13206 / DDX10_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX10
Gene Name Name: DDX10
Organism Homo sapiens (Human)

PRO ID PR:Q13206
DAG View
PRO Name probable ATP-dependent RNA helicase DDX10 (human)
Definition A probable ATP-dependent RNA helicase DDX10 that is encoded in the genome of human.
Short Label hDDX10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13206 (DDX10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19691289, 19664995, 18220336
S7 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 19664995, ...19007248, 18669648
S10 Phosphorylation PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
T197 Phosphorylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
S302 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y305 Phosphorylation HPRD 20068231
S341 O-Glycosylation GlyGen 30379171, 30620550, 35254053
Y358 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K453 Acetylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
S539 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 19007248, ...19691289, 18669648, 19690332, 20068231
T569 Phosphorylation HPRD   PhosphoSitePlus 18691976, 17081983
T577 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S606 O-Glycosylation GlyGen 31373491
S606 Phosphorylation PhosphoSitePlus
T610 O-Glycosylation GlyGen 30379171, 30620550, 35254053
T610 Phosphorylation PhosphoSitePlus
S611 O-Glycosylation GlyGen 30379171, 30620550, 35254053
S611 Phosphorylation PhosphoSitePlus
R626 Methylation PhosphoSitePlus
K649 Sumoylation PhosphoSitePlus
K657 Ubiquitination PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
K666 Acetylation PhosphoSitePlus
K670 Acetylation PhosphoSitePlus
T717 Phosphorylation PhosphoSitePlus
S780 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983
Y801 Phosphorylation HPRD   PhosphoSitePlus 19651622
S803 Phosphorylation PhosphoSitePlus
S804 Phosphorylation HPRD   PhosphoSitePlus 19651622
S807 Phosphorylation HPRD   PhosphoSitePlus 19651622
S809 Phosphorylation HPRD   PhosphoSitePlus 19651622
S829 Phosphorylation HPRD   PhosphoSitePlus 19651622
S831 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S840 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
S875 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T4 R4 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K97 N97 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
K114 T114 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y292 C292 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y292 D292 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y305 H305 Biomuta DOID:363 / uterine cancer [ icgc ]
K446 Q446 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S539 F539 Biomuta DOID:4159 / skin cancer [ cosmic ]
T610 I610 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S611 N611 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R626 K626 Biomuta DOID:4159 / skin cancer [ cosmic ]
K657 N657 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S663 N663 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S831 N831 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S831 R831 Biomuta DOID:4159 / skin cancer [ cosmic ]