iPTMnet Report for Q13200 (PSMD2)
Protein Information
UniProt AC / UniProt ID | Q13200 / PSMD2_HUMAN |
Protein Name | 26S proteasome non-ATPase regulatory subunit 2 |
Gene Name | Name: PSMD2 Synonyms:TRAP2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q13200 |
PRO Name | 26S proteasome non-ATPase regulatory subunit 2 (human) |
Definition | A 26S proteasome non-ATPase regulatory subunit 2 that is encoded in the genome of human. |
Short Label | hPSMD2 |
Category | organism-gene |
Q13200 (PSMD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
S16 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 21406692, 23186163, ... | ||
T24 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 17323924, 20068231 | ||
K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 17323924 | ||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
R79 | Methylation | score1 | PhosphoSitePlus | |||
K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Acetylation | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
R137 | Methylation | score1 | PhosphoSitePlus | |||
C139 | Methylation | score1 | IEDB | 31844290 | ||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
S147 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
T186 | Phosphorylation | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y194 | Phosphorylation | score2 | UniProt | 17323924 | ||
Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
C230 | Methylation | score1 | IEDB | 31844290 | ||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
K350 | Acetylation | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
R357 | Methylation | score1 | PhosphoSitePlus | |||
S361 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 24275569, ... | ||
S363 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y432 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y439 | Phosphorylation | score1 | PhosphoSitePlus | |||
K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
S442 | Phosphorylation | score1 | PhosphoSitePlus | |||
T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
K623 | Ubiquitination | score1 | PhosphoSitePlus | |||
S711 | Phosphorylation | score1 | PhosphoSitePlus | |||
K712 | Ubiquitination | score1 | PhosphoSitePlus | |||
K754 | Ubiquitination | score1 | PhosphoSitePlus | |||
K773 | Ubiquitination | score1 | PhosphoSitePlus | |||
C779 | Methylation | score1 | IEDB | 31844290 | ||
K858 | Ubiquitination | score1 | PhosphoSitePlus | |||
K860 | Ubiquitination | score1 | PhosphoSitePlus | |||
K902 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y906 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S16 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18491316, ... | ||
T24 | Phosphorylation | score0 | HPRD | 20068231 | ||
T86 | Phosphorylation | score0 | HPRD | 20068231 | ||
T90 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S91 | Phosphorylation | score0 | HPRD | 20068231 | ||
S127 | Phosphorylation | score0 | HPRD | 20068231 | ||
S361 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R79 | Q79 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] | |
R79 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S91 | L91 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S91 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K97 | I97 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
C139 | F139 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K189 | R189 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y226 | C226 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
C230 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
Y432 | H432 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
K773 | N773 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K858 | N858 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
Y906 | C906 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |