iPTMnet Report for Q13200 (PSMD2)
Protein Information
| UniProt AC / UniProt ID | Q13200 / PSMD2_HUMAN |
| Protein Name | 26S proteasome non-ATPase regulatory subunit 2 |
| Gene Name | Name: PSMD2 Synonyms:TRAP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q13200 |
| PRO Name | 26S proteasome non-ATPase regulatory subunit 2 (human) |
| Definition | A 26S proteasome non-ATPase regulatory subunit 2 that is encoded in the genome of human. |
| Short Label | hPSMD2 |
| Category | organism-gene |
Q13200 (PSMD2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 21406692, 23186163, ... | ||
| T24 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 17323924, 20068231 | ||
| K27 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S29 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 17323924 | ||
| K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R79 | Methylation | score1 | PhosphoSitePlus | |||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K105 | Acetylation | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R137 | Methylation | score1 | PhosphoSitePlus | |||
| C139 | Methylation | score1 | IEDB | 31844290 | ||
| K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S147 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T186 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y194 | Phosphorylation | score2 | UniProt | 17323924 | ||
| Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C230 | Methylation | score1 | IEDB | 31844290 | ||
| K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K350 | Acetylation | score1 | PhosphoSitePlus | |||
| K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R357 | Methylation | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 24275569, ... | ||
| S363 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y439 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y554 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K623 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S711 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K712 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K754 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K773 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C779 | Methylation | score1 | IEDB | 31844290 | ||
| K858 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K860 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K902 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y906 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S16 | Phosphorylation | score0 | HPRD | 19413330, 18691976, 18491316, ... | ||
| T24 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T86 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T90 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
| S91 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S127 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S361 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R79 | Q79 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] | |
| R79 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S91 | L91 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S91 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K97 | I97 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| C139 | F139 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K189 | R189 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y226 | C226 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| C230 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| Y432 | H432 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| K773 | N773 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K858 | N858 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| Y906 | C906 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View