iPTMnet Report for Q13185 (CBX3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13185 / CBX3_HUMAN
Protein Name Chromobox protein homolog 3
Gene Name Name: CBX3
Organism Homo sapiens (Human)

PRO ID PR:Q13185
DAG View
PRO Name chromobox protein homolog 3 (human)
Definition A chromobox protein homolog 3 that is encoded in the genome of human.
Short Label hCBX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13185 (CBX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K5 Acetylation PhosphoSitePlus
K5 Sumoylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K10 Acetylation PhosphoSitePlus   UniProt 19608861
K10 Sumoylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
K21 Methylation PhosphoSitePlus
K21 Sumoylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K44 Acetylation PhosphoSitePlus   UniProt 19608861
K44 Methylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K50 Acetylation PhosphoSitePlus   UniProt 19608861
K50 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
C69 Methylation IEDB 31844290
S79 Phosphorylation HPRD   PhosphoSitePlus 18077418
K81 Ubiquitination PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
S93 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18691976, 21406692, 16083285, ...17287340, 16964243, 25040935, 19651622, 18669648, 16531993, 24275569, 18212344, 20068231, 17081983
S93 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 16531993
S93 Phosphorylation P22612 (PRKACG) neXtProt 16531993
S93 Phosphorylation P22694 (PRKACB) neXtProt 16531993
S95 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 16083285, ...17287340, 17081983, 18452278, 19651622, 18669648, 24275569, 20166139, 20068231, 18212344
S97 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 17081983, ...19651622, 22067460, 24275569
S99 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17081983, ...24275569
S102 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
K103 Acetylation PhosphoSitePlus
K103 Sumoylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
R119 Methylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
K143 Acetylation PhosphoSitePlus
K143 Methylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
T173 Phosphorylation HPRD   PhosphoSitePlus 18691976, 17081983, 20068231
S176 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...19664994, 19664995, 22067460, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K10 Q10 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T55 R55 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T60 I60 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C69 Y69 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K105 N105 Biomuta DOID:1319 / brain cancer [ icgc ]
K159 N159 Biomuta DOID:363 / uterine cancer [ icgc ]
S176 Y176 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]