iPTMnet Report for Q13148 (TARDBP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13148 / TADBP_HUMAN
Protein Name TAR DNA-binding protein 43
Gene Name Name: TARDBP
Synonyms:TDP43;
Organism Homo sapiens (Human)

PRO ID PR:Q13148
DAG View
PRO Name TAR DNA-binding protein 43 (human)
Definition A TAR DNA-binding protein 43 that is encoded in the genome of human.
Short Label hTARDBP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13148 (TARDBP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus 19285963
S2 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
Y4 Phosphorylation PhosphoSitePlus 19285963
Y4 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
T25 Phosphorylation PhosphoSitePlus 19285963
T25 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
C39 Methylation IEDB 31844290
R42 Methylation PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
C50 Methylation IEDB 31844290
K79 Sumoylation PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K84 Sumoylation PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
T88 Phosphorylation PhosphoSitePlus 19285963
T88 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S91 Phosphorylation PhosphoSitePlus 19285963
S91 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S92 Phosphorylation PhosphoSitePlus 19285963
S92 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
K95 Acetylation PhosphoSitePlus
K95 Sumoylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K114 Sumoylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus 19285963
T116 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
K121 Sumoylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
K140 Acetylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K145 Acetylation PhosphoSitePlus
K145 Sumoylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K160 Sumoylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K176 Sumoylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K181 Methylation PhosphoSitePlus
K181 Sumoylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus   UniProt 19285963, 23186163
S183 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
K192 Acetylation PhosphoSitePlus
K192 Sumoylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
T199 O-Glycosylation GlyGen 16408927, 33214551, 34725712, ...33855783, 34019948, 28510447, 22121020, 34229054
S212 O-Glycosylation GlyGen 16408927, 33214551, 34725712, ...33855783, 34019948, 28510447, 22121020, 34229054
K224 Ubiquitination PhosphoSitePlus
T233 O-Glycosylation GlyGen 16408927, 33214551, 34725712, ...33855783, 34019948, 28510447, 22121020, 34229054
S242 Phosphorylation PhosphoSitePlus 19285963
S242 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S254 Phosphorylation PhosphoSitePlus 19285963
S254 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
K263 Sumoylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus 19285963
S273 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
R275 Methylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus   UniProt 19285963, 23186163, 19690332, ...24275569
S292 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
R293 Methylation PhosphoSitePlus   UniProt 24129315
S305 Phosphorylation PhosphoSitePlus 19285963
S305 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S317 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus 19285963
S342 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S347 Phosphorylation PhosphoSitePlus 19285963
S347 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S350 Phosphorylation PhosphoSitePlus 19285963
S350 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S369 Phosphorylation PhosphoSitePlus 19285963
S369 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S375 Phosphorylation PhosphoSitePlus   RLIMS-P 32778941, 19285963
S375 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S377 Phosphorylation PhosphoSitePlus 19285963
S377 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S379 Phosphorylation PhosphoSitePlus   RLIMS-P 29334120, 19285963, 18546284, ...31306131
S379 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963, 18546284
S379 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 18546284
S387 Phosphorylation PhosphoSitePlus 19285963
S387 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S389 Phosphorylation PhosphoSitePlus 19285963
S389 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S393 Phosphorylation PhosphoSitePlus 19285963
S393 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S395 Phosphorylation PhosphoSitePlus 19285963
S395 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
S403 Phosphorylation PhosphoSitePlus   RLIMS-P 31306131, 29334120, 18546284, ...19285963, 31529970, 19225410
S403 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963, 18546284
S404 Phosphorylation PhosphoSitePlus   RLIMS-P 31306131, 29334120, 18546284, ...19285963, 31529970, 19225410
S404 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963, 18546284
S407 Phosphorylation PhosphoSitePlus 19285963
S407 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 19285963
K408 Sumoylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus   RLIMS-P 31306131, 21062285, 26301107, ...28599005, 30120199, 18546284, 31834878, 19235466, 19285963, 20804554, 26980269, 18656473, 31529970, 29334120, 19225410, 25329970
S409 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 18546284, 19285963, 18656473
S409 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 18546284
S410 Phosphorylation PhosphoSitePlus   RLIMS-P 31306131, 21062285, 26301107, ...28599005, 30120199, 18546284, 31834878, 19235466, 19285963, 20804554, 26980269, 18656473, 31529970, 29334120, 19225410, 25329970
S410 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus 18546284, 19285963, 18656473
S410 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 18546284
Site PTM Type PTM Enzyme Score Source PMID
T88 Phosphorylation HPRD 20068231
S91 Phosphorylation HPRD 17081983, 20068231
S92 Phosphorylation HPRD 17081983, 20068231
T157 Phosphorylation HPRD 17322306


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q04206 (RELA) S536 Q13148 (TARDBP) unknown eFIP 24690380