iPTMnet Report for Q13137 (CALCOCO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13137 / CACO2_HUMAN
Protein Name Calcium-binding and coiled-coil domain-containing protein 2
Gene Name Name: CALCOCO2
Synonyms:NDP52;
Organism Homo sapiens (Human)

PRO ID PR:Q13137
DAG View
PRO Name calcium-binding and coiled-coil domain-containing protein 2 (human)
Definition A calcium-binding and coiled-coil domain-containing protein 2 that is encoded in the genome of human.
Short Label hCALCOCO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13137 (CALCOCO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation PhosphoSitePlus
S85 Phosphorylation IEDB 35494241
K87 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y204 Phosphorylation PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
Y358 Phosphorylation PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S85 L85 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y96 C96 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y96 H96 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K168 N168 Biomuta DOID:1324 / lung cancer [ cosmic ]
K192 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S238 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S355 Y355 Biomuta DOID:363 / uterine cancer [ icgc ]
Y358 C358 Biomuta DOID:1319 / brain cancer [ cosmic ]