iPTMnet Report for Q13136 (PPFIA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q13136 / LIPA1_HUMAN
Protein Name Liprin-alpha-1
Gene Name Name: PPFIA1
Synonyms:LIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q13136
DAG View
PRO Name liprin-alpha-1 (human)
Definition A liprin-alpha-1 that is encoded in the genome of human.
Short Label hPPFIA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q13136 (PPFIA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus   UniProt 23186163
T230 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S234 Phosphorylation PhosphoSitePlus
S238 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S239 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332
S242 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332
S244 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S275 Phosphorylation PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
T302 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus   UniProt 21406692
S458 Phosphorylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K476 Acetylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S530 Phosphorylation PhosphoSitePlus
R535 Methylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Y546 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
T548 Phosphorylation PhosphoSitePlus
S549 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus   UniProt 23186163
S668 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y684 Phosphorylation PhosphoSitePlus
S687 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
S693 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163, 19690332
S697 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus
T701 Phosphorylation PhosphoSitePlus   RLIMS-P 28760951
S708 Phosphorylation PhosphoSitePlus
T734 Phosphorylation PhosphoSitePlus
T735 Phosphorylation PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus
S741 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 15302935
S744 Phosphorylation PhosphoSitePlus
S745 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
K756 Ubiquitination PhosphoSitePlus
T761 Phosphorylation PhosphoSitePlus   UniProt 24275569
S763 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S773 Phosphorylation PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus
S776 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S785 Phosphorylation PhosphoSitePlus
S787 Phosphorylation PhosphoSitePlus
S790 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus
K801 Acetylation PhosphoSitePlus
K804 Acetylation PhosphoSitePlus
S805 Phosphorylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1139 Phosphorylation PhosphoSitePlus
R1150 Methylation PhosphoSitePlus
S1156 Phosphorylation PhosphoSitePlus
T1159 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1171 Phosphorylation PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus
S1174 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S150 Phosphorylation HPRD 17322306, 20068231
S156 Phosphorylation HPRD 17322306
T230 Phosphorylation HPRD 18669648
S238 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S239 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19651622, 20068231
S242 Phosphorylation HPRD 19651622, 18767875, 18669648, ...17081983, 20068231
S244 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S668 Phosphorylation HPRD 19413330
S693 Phosphorylation HPRD 17322306, 19413330
S741 Phosphorylation HPRD 18669648
S745 Phosphorylation HPRD 18669648
S773 Phosphorylation HPRD 18077418
T774 Phosphorylation HPRD 18077418
S776 Phosphorylation HPRD 17525332, 18077418
S785 Phosphorylation HPRD 18077418
S790 Phosphorylation HPRD 18077418
T1159 Phosphorylation HPRD 19664994, 18212344
S1171 Phosphorylation HPRD 19664995
S1172 Phosphorylation HPRD 19413330, 19664995
Site PTM Type PTM Enzyme Score Source PMID
S150 Phosphorylation HPRD 17322306, 20068231
S156 Phosphorylation HPRD 17322306
T230 Phosphorylation HPRD 18669648
S238 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S239 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19651622, 20068231
S242 Phosphorylation HPRD 19651622, 18767875, 18669648, ...17081983, 20068231
S244 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S668 Phosphorylation HPRD 19413330
S693 Phosphorylation HPRD 17322306, 19413330
S741 Phosphorylation HPRD 18669648
S745 Phosphorylation HPRD 18669648
S773 Phosphorylation HPRD 18077418
T774 Phosphorylation HPRD 18077418
S776 Phosphorylation HPRD 17525332, 18077418
S785 Phosphorylation HPRD 18077418
S790 Phosphorylation HPRD 18077418
T1159 Phosphorylation HPRD 19664994, 18212344
S1171 Phosphorylation HPRD 19664995
S1172 Phosphorylation HPRD 19413330, 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S242 F242 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S244 N244 Biomuta DOID:1324 / lung cancer [ cosmic ]
S448 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K467 N467 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K467 E467 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K476 N476 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S668 R668 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S687 F687 Biomuta DOID:4159 / skin cancer [ cosmic ]
S688 L688 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S700 F700 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T701 I701 Biomuta DOID:4159 / skin cancer [ cosmic ]
T701 A701 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S708 I708 Biomuta DOID:3571 / liver cancer [ cosmic ]
S741 F741 Biomuta DOID:4159 / skin cancer [ cosmic ]
T761 I761 Biomuta DOID:4159 / skin cancer [ cosmic ]
S806 F806 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1139 T1139 Biomuta DOID:263 / kidney cancer [ cosmic ]
R1150 H1150 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1174 F1174 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]